功能: catalytic activity:Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).,cofactor:Binds 1 calcium ion per subunit.,disease:Defects in TGM2 are involved in early-onset diabetes type 2.,function:Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.,induction:By retinoic acid.,online information:Tissue transglutaminase entry,similarity:Belongs to the transglutaminase superfamily. Transglutaminase family.,subunit:Monomer.,
相关产品: YT4625,KA3400C,RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm, cytosol . Nucleus . Chromosome . Secreted, extracellular space, extracellular matrix . Cell membrane . Mitochondrion . Mainly localizes to the cytosol (PubMed:9575137). Present at much lower level in the nucleus and chromatin (PubMed:9575137). Also secreted via a non-classical secretion pathway to the extracellular matrix (PubMed:27270573). .; [Isoform 2]: Cytoplasm, perinuclear region .
功能: catalytic activity:Protein glutamine + alkylamine = protein N(5)-alkylglutamine + NH(3).,cofactor:Binds 1 calcium ion per subunit.,disease:Defects in TGM2 are involved in early-onset diabetes type 2.,function:Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.,induction:By retinoic acid.,online information:Tissue transglutaminase entry,similarity:Belongs to the transglutaminase superfamily. Transglutaminase family.,subunit:Monomer.,
相关产品: YT4625,KA3400C,RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm, cytosol . Nucleus . Chromosome . Secreted, extracellular space, extracellular matrix . Cell membrane . Mitochondrion . Mainly localizes to the cytosol (PubMed:9575137). Present at much lower level in the nucleus and chromatin (PubMed:9575137). Also secreted via a non-classical secretion pathway to the extracellular matrix (PubMed:27270573). .; [Isoform 2]: Cytoplasm, perinuclear region .