其他名称: PHLDA1; PHRIP; TDAG51; Pleckstrin homology-like domain family A member 1; Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated
实测条带: 40kD
功能: function:Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.,induction:Induced by homocysteine and other ER stress-inducing reagents. Induced by phorbolester (TPA)/ionomycin, and stimulation of the T-cell receptor (TCR) complex in T-cells.,similarity:Contains 1 PH domain.,subcellular location:Colocalizes with intracellular vesicles.,subunit:Interacts with RPL14, EIF3S7 and PABPC4.,tissue specificity:Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).,
组织表达: Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).
科研货号: PLA018357
TDAG51 Polyclonal Antibody
Catalog NoPLA018357
Product information
基因名称: PHLDA1
蛋白名称: Pleckstrin homology-like domain family A member 1
其他名称: PHLDA1; PHRIP; TDAG51; Pleckstrin homology-like domain family A member 1; Apoptosis-associated nuclear protein; Proline- and glutamine-rich protein; PQ-rich protein; PQR protein; Proline- and histidine-rich protein; T-cell death-associated
实测条带: 40kD
功能: function:Seems to be involved in regulation of apoptosis. May be involved in detachment-mediated programmed cell death. May mediate apoptosis during neuronal development. May be involved in regulation of anti-apoptotic effects of IGF1. May be involved in translational regulation.,induction:Induced by homocysteine and other ER stress-inducing reagents. Induced by phorbolester (TPA)/ionomycin, and stimulation of the T-cell receptor (TCR) complex in T-cells.,similarity:Contains 1 PH domain.,subcellular location:Colocalizes with intracellular vesicles.,subunit:Interacts with RPL14, EIF3S7 and PABPC4.,tissue specificity:Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).,
组织表达: Widely expressed with highest levels in pancreas. Strongly expressed by benign melanocytic nevi, and progressively reduced expressed in primary and metastatic melanomas (at protein level).