TANK Polyclonal Antibody

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商品货号： PLA018320

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： TANK
蛋白名称： TRAF family member-associated NF-kappa-B activator
Human_gene_id： 10010
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10010
Human_swiss_prot_no： Q92844
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q92844/entry
Mouse_gene_id： 21353
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21353
Mouse_swiss_prot_no： P70347
Mouse_swiss_link： http://www.uniprot.org/uniprot/P70347
特异性： TANK Polyclonal Antibody detects endogenous levels of TANK protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TANK; ITRAF; TRAF2; TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; I-TRAF
实测条带： 48kD
信号通路： RIG-I-like receptor;
功能： function:Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.,PTM:Phosphorylated by IKBKE.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Interacts with TBK1 (via TRAF-C domain). Interacts with TRAF1 (via TRAF-C domain). Interacts with TRAF2 (via TRAF-C domain); the interaction is disrupted by the phosphorylation of TANK by IKBKE. Interacts with TRAF3 (via TRAF-C domain); the interaction with TRAF3 is weaker than the interactions with TRAF1 and TRAF3. Interacts with IKBKG; the interaction is enhanced by IKBKE and TBK1. Part of a ternary complex consisting of TANK, IKBKB and IKBKG.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm.
组织表达： Ubiquitous.
科研货号： PLA018320

TANK Polyclonal Antibody

Catalog No PLA018320

Product information

基因名称： TANK
蛋白名称： TRAF family member-associated NF-kappa-B activator
Human_gene_id： 10010
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10010
Human_swiss_prot_no： Q92844
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q92844/entry
Mouse_gene_id： 21353
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21353
Mouse_swiss_prot_no： P70347
Mouse_swiss_link： http://www.uniprot.org/uniprot/P70347
特异性： TANK Polyclonal Antibody detects endogenous levels of TANK protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:10000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： TANK; ITRAF; TRAF2; TRAF family member-associated NF-kappa-B activator; TRAF-interacting protein; I-TRAF
实测条带： 48kD
信号通路： RIG-I-like receptor;
功能： function:Acts as a regulator of TRAF function by maintaining them in a latent state. Overexpression inhibits TRAF2-mediated NF-kappa-B activation signaled by CD40, TNFR1 and TNFR2. Blocks TRAF2 binding to LMP1 and inhibits LMP1-mediated NF-kappa-B activation. May be involved in I-kappa-B-kinase (IKK) regulation; may function as an adapter for kinases such as TBK1 or IKBKE that can modulate IKK activity.,PTM:Phosphorylated by IKBKE.,similarity:Contains 1 C2H2-type zinc finger.,subunit:Interacts with TBK1 (via TRAF-C domain). Interacts with TRAF1 (via TRAF-C domain). Interacts with TRAF2 (via TRAF-C domain); the interaction is disrupted by the phosphorylation of TANK by IKBKE. Interacts with TRAF3 (via TRAF-C domain); the interaction with TRAF3 is weaker than the interactions with TRAF1 and TRAF3. Interacts with IKBKG; the interaction is enhanced by IKBKE and TBK1. Part of a ternary complex consisting of TANK, IKBKB and IKBKG.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm.
组织表达： Ubiquitous.
科研货号： PLA018320

Hunan UPT Biotechnology Co.,Ltd

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