功能： disease:A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.,function:RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).,PTM:Arg-206 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the RRM TET family.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1.,tissue specificity:Ubiquitous. Observed in all fetal and adult tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles from the nucleus to the cytoplasm.
组织表达： Ubiquitous. Observed in all fetal and adult tissues.
功能： disease:A chromosomal aberration involving TAF15/TAF2N is found in a form of extraskeletal myxoid chondrosarcomas (EMC). Translocation t(9;17)(q22;q11) with NR4A3.,function:RNA and ssDNA-binding protein that may play specific roles during transcription initiation at distinct promoters. Can enter the preinitiation complex together with the RNA polymerase II (Pol II).,PTM:Arg-206 is dimethylated, probably to asymmetric dimethylarginine.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the RRM TET family.,similarity:Contains 1 RanBP2-type zinc finger.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subunit:Belongs to the RNA polymerase II (Pol II) transcriptional multiprotein complex, together with the TATA-binding protein (TBP) and other TBP-associated factors (TAF(II)s). Binds SF1.,tissue specificity:Ubiquitous. Observed in all fetal and adult tissues.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Cytoplasm . Shuttles from the nucleus to the cytoplasm.
组织表达： Ubiquitous. Observed in all fetal and adult tissues.
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