Synuclein-β Polyclonal Antibody

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商品货号： PLA018280

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SNCB
蛋白名称： Beta-synuclein
Human_gene_id： 6620
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6620
Human_swiss_prot_no： Q16143
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q16143/entry
Mouse_gene_id： 104069
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104069
Mouse_swiss_prot_no： Q91ZZ3
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q91ZZ3
Rat_gene_id： 113893
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113893
Rat_swiss_prot_no： Q63754
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63754
特异性： Synuclein-β Polyclonal Antibody detects endogenous levels of Synuclein-β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SNCB; Beta-synuclein
实测条带： 14kD
功能： disease:Brain iron accumulation type 1 (NBIA1, also called Hallervorden-Spatz syndrome), a rare neuroaxonal dystrophy, is histologically characterized by axonal spheroids, iron deposition, Lewy body (LB)-like intraneuronal inclusions, glial inclusions and neurofibrillary tangles. SNCB is found in spheroids but not in inclusions.,function:Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a TP53/p53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.,PTM:Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.,similarity:Belongs to the synuclein family.,tissue specificity:Expressed predominantly in brain; concentrated in presynaptic nerve terminals.,
相关产品： YT4498,KA3387C,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm.
组织表达： Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
科研货号： PLA018280

Synuclein-β Polyclonal Antibody

Catalog No PLA018280

Product information

基因名称： SNCB
蛋白名称： Beta-synuclein
Human_gene_id： 6620
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6620
Human_swiss_prot_no： Q16143
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q16143/entry
Mouse_gene_id： 104069
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=104069
Mouse_swiss_prot_no： Q91ZZ3
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q91ZZ3
Rat_gene_id： 113893
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=113893
Rat_swiss_prot_no： Q63754
Rat_swiss_link： http://www.uniprot.org/uniprot/Q63754
特异性： Synuclein-β Polyclonal Antibody detects endogenous levels of Synuclein-β protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SNCB; Beta-synuclein
实测条带： 14kD
功能： disease:Brain iron accumulation type 1 (NBIA1, also called Hallervorden-Spatz syndrome), a rare neuroaxonal dystrophy, is histologically characterized by axonal spheroids, iron deposition, Lewy body (LB)-like intraneuronal inclusions, glial inclusions and neurofibrillary tangles. SNCB is found in spheroids but not in inclusions.,function:Non-amyloid component of senile plaques found in Alzheimer disease. Could act as a regulator of SNCA aggregation process. Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a TP53/p53-dependent manner. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA. Not found in the Lewy bodies associated with Parkinson disease.,PTM:Phosphorylated. Phosphorylation by G-protein coupled receptor kinases (GRK) is more efficient than phosphorylation by CK1, CK2 and CaM-kinase II.,similarity:Belongs to the synuclein family.,tissue specificity:Expressed predominantly in brain; concentrated in presynaptic nerve terminals.,
相关产品： YT4498,KA3387C,RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm.
组织表达： Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
科研货号： PLA018280

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