Spectrin β II Polyclonal Antibody

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商品货号： PLA018190

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： SPTBN1
蛋白名称： Spectrin beta chain non-erythrocytic 1
Human_gene_id： 6711
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6711
Human_swiss_prot_no： Q01082
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q01082/entry
Mouse_gene_id： 20742
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20742
Mouse_swiss_prot_no： Q62261
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62261
特异性： Spectrin β II Polyclonal Antibody detects endogenous levels of Spectrin β II protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SPTBN1; SPTB2; Spectrin beta chain; non-erythrocytic 1; Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1
实测条带： 275kD
功能： function:Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.,PTM:Isoform 2 is phosphorylated on Ser-8 and Ser-10.,similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 17 spectrin repeats.,similarity:Contains 2 CH (calponin-homology) domains.,subcellular location:Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes.,subunit:Like erythrocyte spectrin, the spectrin-like proteins are capable to form dimers which can further associate to tetramers. The short form cannot bind to the axonal protein fodaxin. Interacts with ANK2.,tissue specificity:Isoform 2 is present in brain, lung and kidney (at protein level).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, M line . Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. .; [Isoform 2]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
组织表达： Isoform 2 is present in brain, lung and kidney (at protein level).
科研货号： PLA018190

Spectrin β II Polyclonal Antibody

Catalog No PLA018190

Product information

基因名称： SPTBN1
蛋白名称： Spectrin beta chain non-erythrocytic 1
Human_gene_id： 6711
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=6711
Human_swiss_prot_no： Q01082
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q01082/entry
Mouse_gene_id： 20742
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=20742
Mouse_swiss_prot_no： Q62261
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q62261
特异性： Spectrin β II Polyclonal Antibody detects endogenous levels of Spectrin β II protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： SPTBN1; SPTB2; Spectrin beta chain; non-erythrocytic 1; Beta-II spectrin; Fodrin beta chain; Spectrin, non-erythroid beta chain 1
实测条带： 275kD
功能： function:Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane.,PTM:Isoform 2 is phosphorylated on Ser-8 and Ser-10.,similarity:Belongs to the spectrin family.,similarity:Contains 1 PH domain.,similarity:Contains 17 spectrin repeats.,similarity:Contains 2 CH (calponin-homology) domains.,subcellular location:Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes.,subunit:Like erythrocyte spectrin, the spectrin-like proteins are capable to form dimers which can further associate to tetramers. The short form cannot bind to the axonal protein fodaxin. Interacts with ANK2.,tissue specificity:Isoform 2 is present in brain, lung and kidney (at protein level).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton . Cytoplasm, myofibril, sarcomere, M line . Colocalizes with ANK2 in a distinct intracellular compartment of neonatal cardiomyocytes. .; [Isoform 2]: Cell membrane ; Peripheral membrane protein ; Cytoplasmic side .
组织表达： Isoform 2 is present in brain, lung and kidney (at protein level).
科研货号： PLA018190

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