其他名称: RREB1; FINB; Ras-responsive element-binding protein 1; RREB-1; Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Zinc finger motif enhancer-binding protein 1; Zep-1
实测条带: 180kD
功能: function:Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Numerous sequencing errors.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 15 C2H2-type zinc fingers.,subunit:Interacts with NEUROD1 and AR.,tissue specificity:Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus speckle .
组织表达: Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.
其他名称: RREB1; FINB; Ras-responsive element-binding protein 1; RREB-1; Finger protein in nuclear bodies; Raf-responsive zinc finger protein LZ321; Zinc finger motif enhancer-binding protein 1; Zep-1
实测条带: 180kD
功能: function:Transcription factor that binds specifically to the RAS-responsive elements (RRE) of gene promoters. May be involved in Ras/Raf-mediated cell differentiation by enhancing calcitonin expression. Represses the angiotensinogen gene. Negatively regulates the transcriptional activity of AR. Potentiates the transcriptional activity of NEUROD1.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,sequence caution:Contaminating sequence. Potential poly-A sequence.,sequence caution:Numerous sequencing errors.,sequence caution:Translation N-terminally extended.,similarity:Belongs to the krueppel C2H2-type zinc-finger protein family.,similarity:Contains 15 C2H2-type zinc fingers.,subunit:Interacts with NEUROD1 and AR.,tissue specificity:Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus speckle .
组织表达: Expressed in heart, placenta, lung, liver, skeletal muscle, kidney and pancreas. Not found in the brain.