RNF138 Polyclonal Antibody

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商品货号： PLA017990

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： RNF138
蛋白名称： E3 ubiquitin-protein ligase RNF138
Human_gene_id： 51444
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51444
Human_swiss_prot_no： Q8WVD3
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8WVD3/entry
Mouse_gene_id： 56515
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56515
Mouse_swiss_prot_no： Q9CQE0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQE0
Rat_gene_id： 94196
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94196
Rat_swiss_prot_no： Q99PD2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q99PD2
特异性： RNF138 Polyclonal Antibody detects endogenous levels of RNF138 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RNF138; NARF; HSD-4; HSD4; E3 ubiquitin-protein ligase RNF138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein; hNARF; RING finger protein 138
实测条带： 28kD
功能： domain:The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.,function:E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.,pathway:Protein modification; protein ubiquitination.,PTM:Auto-ubiquitinated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with nlk.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Chromosome . Recruited at DNA damage sites (PubMed:26502055). Localizes to sites of double-strand break: localization to double-strand break sites is mediated by the zinc fingers (PubMed:26502055, PubMed:26502057). .
组织表达： Placenta,Testis,Uterus,
tag： hot
科研货号： PLA017990

RNF138 Polyclonal Antibody

Catalog No PLA017990

Product information

基因名称： RNF138
蛋白名称： E3 ubiquitin-protein ligase RNF138
Human_gene_id： 51444
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51444
Human_swiss_prot_no： Q8WVD3
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8WVD3/entry
Mouse_gene_id： 56515
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=56515
Mouse_swiss_prot_no： Q9CQE0
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CQE0
Rat_gene_id： 94196
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=94196
Rat_swiss_prot_no： Q99PD2
Rat_swiss_link： http://www.uniprot.org/uniprot/Q99PD2
特异性： RNF138 Polyclonal Antibody detects endogenous levels of RNF138 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RNF138; NARF; HSD-4; HSD4; E3 ubiquitin-protein ligase RNF138; Nemo-like kinase-associated RING finger protein; NLK-associated RING finger protein; hNARF; RING finger protein 138
实测条带： 28kD
功能： domain:The RING-type zinc finger domain mediates binding to an E2 ubiquitin-conjugating enzyme.,function:E3 ubiquitin-protein ligase. Together with NLK, involved in the ubiquitination and degradation of TCF/LEF. Also exhibits auto-ubiquitination activity in combination with UBE2K. May act as a negative regulator in the Wnt/beta-catenin-mediated signaling pathway.,pathway:Protein modification; protein ubiquitination.,PTM:Auto-ubiquitinated.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with nlk.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Chromosome . Recruited at DNA damage sites (PubMed:26502055). Localizes to sites of double-strand break: localization to double-strand break sites is mediated by the zinc fingers (PubMed:26502055, PubMed:26502057). .
组织表达： Placenta,Testis,Uterus,
tag： hot
科研货号： PLA017990

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