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Rho A Polyclonal Antibody
商品货号: PLA017915
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: RHOA
  • 蛋白名称: Transforming protein RhoA
  • Human_gene_id: 387
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=387
  • Human_swiss_prot_no: P61586
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P61586/entry
  • Mouse_gene_id: 11848
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11848
  • Mouse_swiss_prot_no: Q9QUI0
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9QUI0
  • Rat_gene_id: 117273
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117273
  • Rat_swiss_prot_no: P61589
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P61589
  • 特异性: Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RHOA; ARH12; ARHA; RHO12; Transforming protein RhoA; Rho cDNA clone 12; h12
  • 实测条带: 22kD
  • 信号通路: Chemokine;Vascular smooth muscle contraction;WNT;WNT-T CELLTGF-beta;Axon guidance;Focal adhesion;Adherens_Junction;Adherens_Junction;T_Cell_Receptor;Leukocyte transendothelial migration;Neurotrophin;Regulates Actin and Cytoskeleton;Pathogenic Escherichia coli infection;Pathways in cancer;
  • 功能: cofactor:Magnesium.,domain:The basic-rich region is essential for yopT recognition and cleavage.,function:Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP.,PTM:Cleaved by yopT protease when the cell is infected by some Yersinia pathogens. This removes the lipid attachment, and leads to its displacement from plasma membrane and to subsequent cytoskeleton cleavage.,PTM:Substrate for botulinum ADP-ribosyltransferase.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with RGNEF (By similarity). Binds PRKCL1, ROCK1 and ROCK2. Interacts with ARHGEF2, ARHGEF3, NET1 and RTKN. Interacts with PLCE1 and AKAP13. Interacts with human respiratory syncytial virus (HRSV) protein F; this interaction facilitates virus-induced syncytium formation.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex . Midbody. Cell projection, lamellipodium . Cell projection, dendrite . Nucleus . Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner. .
  • 组织表达: Adipose tissue,Brain,Colon,Mammary cancer,Oesophageal carcinoma,Placenta,Re
  • tag: hot
  • 科研货号: PLA017915
Rho A Polyclonal Antibody
Catalog No PLA017915
Product information
  • 基因名称: RHOA
  • 蛋白名称: Transforming protein RhoA
  • Human_gene_id: 387
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=387
  • Human_swiss_prot_no: P61586
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P61586/entry
  • Mouse_gene_id: 11848
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11848
  • Mouse_swiss_prot_no: Q9QUI0
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9QUI0
  • Rat_gene_id: 117273
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=117273
  • Rat_swiss_prot_no: P61589
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P61589
  • 特异性: Rho A Polyclonal Antibody detects endogenous levels of Rho A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IF 1:50-200 WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RHOA; ARH12; ARHA; RHO12; Transforming protein RhoA; Rho cDNA clone 12; h12
  • 实测条带: 22kD
  • 信号通路: Chemokine;Vascular smooth muscle contraction;WNT;WNT-T CELLTGF-beta;Axon guidance;Focal adhesion;Adherens_Junction;Adherens_Junction;T_Cell_Receptor;Leukocyte transendothelial migration;Neurotrophin;Regulates Actin and Cytoskeleton;Pathogenic Escherichia coli infection;Pathways in cancer;
  • 功能: cofactor:Magnesium.,domain:The basic-rich region is essential for yopT recognition and cleavage.,function:Regulates a signal transduction pathway linking plasma membrane receptors to the assembly of focal adhesions and actin stress fibers. Serves as a target for the yopT cysteine peptidase from Yersinia pestis, vector of the plague, and Yersinia pseudotuberculosis, which causes gastrointestinal disorders. May be an activator of PLCE1. Activated by ARHGEF2, which promotes the exchange of GDP for GTP.,PTM:Cleaved by yopT protease when the cell is infected by some Yersinia pathogens. This removes the lipid attachment, and leads to its displacement from plasma membrane and to subsequent cytoskeleton cleavage.,PTM:Substrate for botulinum ADP-ribosyltransferase.,similarity:Belongs to the small GTPase superfamily. Rho family.,subunit:Interacts with RGNEF (By similarity). Binds PRKCL1, ROCK1 and ROCK2. Interacts with ARHGEF2, ARHGEF3, NET1 and RTKN. Interacts with PLCE1 and AKAP13. Interacts with human respiratory syncytial virus (HRSV) protein F; this interaction facilitates virus-induced syncytium formation.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Lipid-anchor; Cytoplasmic side. Cytoplasm, cytoskeleton. Cleavage furrow. Cytoplasm, cell cortex . Midbody. Cell projection, lamellipodium . Cell projection, dendrite . Nucleus . Localized to cell-cell contacts in calcium-treated keratinocytes (By similarity). Translocates to the equatorial region before furrow formation in a ECT2-dependent manner. Localizes to the equatorial cell cortex (at the site of the presumptive furrow) in early anaphase in an activated form and in a myosin- and actin-independent manner. .
  • 组织表达: Adipose tissue,Brain,Colon,Mammary cancer,Oesophageal carcinoma,Placenta,Re
  • tag: hot
  • 科研货号: PLA017915
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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