其他名称: REPS1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1
实测条带: 80kD
功能: function:May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.,PTM:EGF stimulates phosphorylation on Tyr-residues.,similarity:Contains 1 EF-hand domain.,similarity:Contains 1 EH domain.,subunit:Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
组织表达: Widely expressed with highest levels in heart and testis.
科研货号: PLA017893
REPS1 Polyclonal Antibody
Catalog NoPLA017893
Product information
基因名称: REPS1
蛋白名称: RalBP1-associated Eps domain-containing protein 1
其他名称: REPS1; RalBP1-associated Eps domain-containing protein 1; RalBP1-interacting protein 1
实测条带: 80kD
功能: function:May coordinate the cellular actions of activated EGF receptors and Ral-GTPases.,PTM:EGF stimulates phosphorylation on Tyr-residues.,similarity:Contains 1 EF-hand domain.,similarity:Contains 1 EH domain.,subunit:Homodimer (Potential). Interacts with RAB11FIP2. Interacts with RALBP1, CRK and GRB2. Binding to RALBP1 does not affect its Ral-binding activity. Forms a complex with the SH3 domains of CRK and GRB2 which may link it to an EGF-responsive tyrosine kinase.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Membrane, clathrin-coated pit . Colocalize with ITSN1 at the plasma membrane in structures that are most probably clathrin-coated pits.
组织表达: Widely expressed with highest levels in heart and testis.