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Repo-Man Polyclonal Antibody
商品货号: PLA017892
适 应 性:
WB IHC IF ELISA
¥600元
规格:
在线咨询
MSDS
说明书
商品描述
  • 基因名称: CDCA2
  • 蛋白名称: Cell division cycle-associated protein 2
  • Human_gene_id: 157313
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157313
  • Human_swiss_prot_no: Q69YH5
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q69YH5/entry
  • Mouse_swiss_prot_no: Q14B71
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q14B71
  • 特异性: Repo-Man Polyclonal Antibody detects endogenous levels of Repo-Man protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDCA2; Cell division cycle-associated protein 2; Recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
  • 实测条带: 120-130kD
  • 功能: function:Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.,PTM:Phosphorylated by CDK1. May regulate its subcellular location.,subcellular location:Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.,subunit:Interacts with PPP1CC.,tissue specificity:Ubiquitously expressed.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.
  • 组织表达: Ubiquitously expressed.
  • tag: hot
  • 科研货号: PLA017892
Repo-Man Polyclonal Antibody
Catalog No PLA017892
Product information
  • 基因名称: CDCA2
  • 蛋白名称: Cell division cycle-associated protein 2
  • Human_gene_id: 157313
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=157313
  • Human_swiss_prot_no: Q69YH5
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q69YH5/entry
  • Mouse_swiss_prot_no: Q14B71
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q14B71
  • 特异性: Repo-Man Polyclonal Antibody detects endogenous levels of Repo-Man protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDCA2; Cell division cycle-associated protein 2; Recruits PP1 onto mitotic chromatin at anaphase protein; Repo-Man
  • 实测条带: 120-130kD
  • 功能: function:Regulator of chromosome structure during mitosis required for condensin-depleted chromosomes to retain their compact architecture through anaphase. Acts by mediating the recruitment of phopsphatase PP1-gamma subunit (PPP1CC) to chromatin at anaphase and into the following interphase. At anaphase onset, its association with chromatin targets a pool of PPP1CC to dephosphorylate substrates.,PTM:Phosphorylated by CDK1. May regulate its subcellular location.,subcellular location:Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.,subunit:Interacts with PPP1CC.,tissue specificity:Ubiquitously expressed.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Excluded from the nucleolus. Present in nucleoplasm throughout the G1, S and G2 stages of the cell cycle. During M phase, it becomes diffuse throughout the cell as the nuclear membrane breaks down, and faintly accumulates later on metaphase chromatin. As the cell progresses to anaphase, it accumulates on chromatin.
  • 组织表达: Ubiquitously expressed.
  • tag: hot
  • 科研货号: PLA017892
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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