Renin Receptor Polyclonal Antibody

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商品货号： PLA017887

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ATP6AP2
蛋白名称： Renin receptor
Human_gene_id： 10159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10159
Human_swiss_prot_no： O75787
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75787/entry
Mouse_gene_id： 70495
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70495
Mouse_swiss_prot_no： Q9CYN9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CYN9
Rat_gene_id： 302526
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=302526
Rat_swiss_prot_no： Q6AXS4
Rat_swiss_link： http://www.uniprot.org/uniprot/Q6AXS4
特异性： Renin Receptor Polyclonal Antibody detects endogenous levels of Renin Receptor protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072; Renin receptor; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryoni
实测条带： 39kD
功能： disease:Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.,function:Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).,PTM:Phosphorylated.,subunit:Interacts with renin and the vacuolar proton-ATPase.,tissue specificity:Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.,
相关产品： YT4048,KA3492C,RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Single-pass type I membrane protein . Cell projection, dendritic spine membrane ; Single-pass type I membrane protein . Cell projection, axon . Endosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein .
组织表达： Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
科研货号： PLA017887

Renin Receptor Polyclonal Antibody

Catalog No PLA017887

Product information

基因名称： ATP6AP2
蛋白名称： Renin receptor
Human_gene_id： 10159
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10159
Human_swiss_prot_no： O75787
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75787/entry
Mouse_gene_id： 70495
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70495
Mouse_swiss_prot_no： Q9CYN9
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9CYN9
Rat_gene_id： 302526
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=302526
Rat_swiss_prot_no： Q6AXS4
Rat_swiss_link： http://www.uniprot.org/uniprot/Q6AXS4
特异性： Renin Receptor Polyclonal Antibody detects endogenous levels of Renin Receptor protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072; Renin receptor; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryoni
实测条带： 39kD
功能： disease:Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.,function:Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).,PTM:Phosphorylated.,subunit:Interacts with renin and the vacuolar proton-ATPase.,tissue specificity:Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.,
相关产品： YT4048,KA3492C,RS0001,RS0002,YM3028,YM3029
细胞定位： Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Single-pass type I membrane protein . Cell projection, dendritic spine membrane ; Single-pass type I membrane protein . Cell projection, axon . Endosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein .
组织表达： Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
科研货号： PLA017887

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