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Renin Receptor Polyclonal Antibody
商品货号: PLA017887
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: ATP6AP2
  • 蛋白名称: Renin receptor
  • Human_gene_id: 10159
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10159
  • Human_swiss_prot_no: O75787
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O75787/entry
  • Mouse_gene_id: 70495
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70495
  • Mouse_swiss_prot_no: Q9CYN9
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9CYN9
  • Rat_gene_id: 302526
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=302526
  • Rat_swiss_prot_no: Q6AXS4
  • Rat_swiss_link: http://www.uniprot.org/uniprot/Q6AXS4
  • 特异性: Renin Receptor Polyclonal Antibody detects endogenous levels of Renin Receptor protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072; Renin receptor; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryoni
  • 实测条带: 39kD
  • 功能: disease:Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.,function:Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).,PTM:Phosphorylated.,subunit:Interacts with renin and the vacuolar proton-ATPase.,tissue specificity:Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.,
  • 相关产品: YT4048,KA3492C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Single-pass type I membrane protein . Cell projection, dendritic spine membrane ; Single-pass type I membrane protein . Cell projection, axon . Endosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein .
  • 组织表达: Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
  • 科研货号: PLA017887
Renin Receptor Polyclonal Antibody
Catalog No PLA017887
Product information
  • 基因名称: ATP6AP2
  • 蛋白名称: Renin receptor
  • Human_gene_id: 10159
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10159
  • Human_swiss_prot_no: O75787
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O75787/entry
  • Mouse_gene_id: 70495
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=70495
  • Mouse_swiss_prot_no: Q9CYN9
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9CYN9
  • Rat_gene_id: 302526
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=302526
  • Rat_swiss_prot_no: Q6AXS4
  • Rat_swiss_link: http://www.uniprot.org/uniprot/Q6AXS4
  • 特异性: Renin Receptor Polyclonal Antibody detects endogenous levels of Renin Receptor protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: ATP6AP2; ATP6IP2; CAPER; ELDF10; HT028; MSTP009; PSEC0072; Renin receptor; ATPase H(+)-transporting lysosomal accessory protein 2; ATPase H(+)-transporting lysosomal-interacting protein 2; ER-localized type I transmembrane adaptor; Embryoni
  • 实测条带: 39kD
  • 功能: disease:Defects in ATP6AP2 are a cause of mental retardation X-linked with epilepsy (MRXE) [MIM:300423]. MRXE is a syndromic mental retardation. Patients manifest mild to moderate mental retardation associated with epilepsy, delays in motor milestones and speech acquisition in infancy.,function:Functions as a renin and prorenin cellular receptor. May mediate renin-dependent cellular responses by activating ERK1 and ERK2. By increasing the catalytic efficiency of renin in AGT/angiotensinogen conversion to angiotensin I, it may also play a role in the renin-angiotensin system (RAS).,PTM:Phosphorylated.,subunit:Interacts with renin and the vacuolar proton-ATPase.,tissue specificity:Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncitiotrophoblast cells in the mature fetal placenta.,
  • 相关产品: YT4048,KA3492C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endoplasmic reticulum membrane ; Single-pass type I membrane protein . Lysosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, autophagosome membrane ; Single-pass type I membrane protein . Cell projection, dendritic spine membrane ; Single-pass type I membrane protein . Cell projection, axon . Endosome membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, clathrin-coated vesicle membrane ; Single-pass type I membrane protein . Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane ; Single-pass type I membrane protein .
  • 组织表达: Expressed in brain, heart, placenta, liver, kidney and pancreas. Barely detectable in lung and skeletal muscles. In the kidney cortex it is restricted to the mesangium of glomeruli. In the coronary and kidney artery it is expressed in the subendothelium, associated to smooth muscles where it colocalizes with REN. Expressed in vascular structures and by syncytiotrophoblast cells in the mature fetal placenta.
  • 科研货号: PLA017887
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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