其他名称: REG4; GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
分子量: 18kD
功能: function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.,induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum.,online information:Regenerating protein IV,similarity:Contains 1 C-type lectin domain.,tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.
其他名称: REG4; GISP; RELP; Regenerating islet-derived protein 4; REG-4; Gastrointestinal secretory protein; REG-like protein; Regenerating islet-derived protein IV; Reg IV
分子量: 18kD
功能: function:May be involved in inflammatory and metaplastic responses of the gastrointestinal epithelium.,induction:Up-regulated by mucosal injury from active Crohn's disease or ulcerative colitis. Up-regulated in colorectal tumors. Up-regulated in epithelial cells at regenerating margins of peptic ulcers in the stomach and duodenum.,online information:Regenerating protein IV,similarity:Contains 1 C-type lectin domain.,tissue specificity:Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentialy expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted .
组织表达: Highly expressed in the gastrointestinal tract including the duodenum, jejunum, ileum, ileocecum, appendix, descending colon, pancreas and small intestine. Weakly expressed in normal colon and stomach. Strongly expressed in most colorectal tumors than in normal colon. Preferentially expressed in mucinous tumors and in some cases neuro-endocrine tumors. Expressed in mucus-secreting cells and enterocyte-like cells. In small intestine expressed at the basal perinuclear zone of goblet cells.