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RDM1 Polyclonal Antibody
商品货号: PLA017874
适 应 性: 人,大鼠,小鼠,
IHC IF ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: RDM1
  • 蛋白名称: RAD52 motif-containing protein 1
  • Human_gene_id: 201299
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=201299
  • Human_swiss_prot_no: Q8NG50
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q8NG50/entry
  • Mouse_swiss_prot_no: Q9CQK3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9CQK3
  • 特异性: RDM1 Polyclonal Antibody detects endogenous levels of RDM1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RDM1; RAD52B; RAD52 motif-containing protein 1; RAD52 homolog B
  • 分子量: 32kD
  • 功能: caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:C-terminal half (amino acids 134-284) contains cytoplasmic retention domains as well as determinants involved in its stress-induced nucleolar accumulation.,function:May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.,induction:Heat-shock stress up-regulated mRNA expression of isoform 10 and isoform 11. Heat-shock stress down-regulated short N-terminal mRNA expression of isoform 2, isoform 4, isoform 6 and isoform 9.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Isoform 1 is predominantly cytoplasmic. Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.,subunit:Homodimer.,tissue specificity:Expressed in testis.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm . Nucleus, nucleolus . Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.; [Isoform 1]: Cytoplasm. Nucleus, PML body. Nucleus, Cajal body. Isoform 1 is predominantly cytoplasmic. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress.
  • 组织表达: Expressed in testis.
  • 科研货号: PLA017874
RDM1 Polyclonal Antibody
Catalog No PLA017874
Product information
  • 基因名称: RDM1
  • 蛋白名称: RAD52 motif-containing protein 1
  • Human_gene_id: 201299
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=201299
  • Human_swiss_prot_no: Q8NG50
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q8NG50/entry
  • Mouse_swiss_prot_no: Q9CQK3
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q9CQK3
  • 特异性: RDM1 Polyclonal Antibody detects endogenous levels of RDM1 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RDM1; RAD52B; RAD52 motif-containing protein 1; RAD52 homolog B
  • 分子量: 32kD
  • 功能: caution:The sequence shown here is derived from an Ensembl automatic analysis pipeline and should be considered as preliminary data.,domain:C-terminal half (amino acids 134-284) contains cytoplasmic retention domains as well as determinants involved in its stress-induced nucleolar accumulation.,function:May confer resistance to the antitumor agent cisplatin. Binds to DNA and RNA.,induction:Heat-shock stress up-regulated mRNA expression of isoform 10 and isoform 11. Heat-shock stress down-regulated short N-terminal mRNA expression of isoform 2, isoform 4, isoform 6 and isoform 9.,similarity:Contains 1 RRM (RNA recognition motif) domain.,subcellular location:Isoform 1 is predominantly cytoplasmic. Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.,subunit:Homodimer.,tissue specificity:Expressed in testis.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Cytoplasm . Nucleus, nucleolus . Isoform 3 and isoform 10 are predominantly nuclear and nucleolar. After treatment with proteasomal inhibitors and mild heat-shock stress, isoform 1, isoform 3, isoform 5, isoform 7, isoform 8 and isoform 10 are relocalized to the nucleolus as dot-like or irregular subnuclear structures. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress. Isoform 3, but not isoform 1 and isoform 5, is relocalized in nucleolar caps during transcriptional arrest.; [Isoform 1]: Cytoplasm. Nucleus, PML body. Nucleus, Cajal body. Isoform 1 is predominantly cytoplasmic. Isoform 1 colocalized with nuclear promyelocytic leukemia (PML) and Cajal bodies (CB); this association with nuclear bodies is enhanced in response to proteotoxic stress.
  • 组织表达: Expressed in testis.
  • 科研货号: PLA017874
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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