其他名称: RAP1GAP; KIAA0474; RAP1GA1; Rap1 GTPase-activating protein 1; Rap1GAP; Rap1GAP1
实测条带: 73kD
功能: function:GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.,induction:By 12-O-tetradecanoylphorbol-13-acetate (TPA) in promyelocytic HL-60 cells.,similarity:Contains 1 GoLoco domain.,similarity:Contains 1 Rap-GAP domain.,tissue specificity:Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.,
组织表达: Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.
其他名称: RAP1GAP; KIAA0474; RAP1GA1; Rap1 GTPase-activating protein 1; Rap1GAP; Rap1GAP1
实测条带: 73kD
功能: function:GTPase activator for the nuclear Ras-related regulatory protein RAP-1A (KREV-1), converting it to the putatively inactive GDP-bound state.,induction:By 12-O-tetradecanoylphorbol-13-acetate (TPA) in promyelocytic HL-60 cells.,similarity:Contains 1 GoLoco domain.,similarity:Contains 1 Rap-GAP domain.,tissue specificity:Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.,
组织表达: Significant expression seen in the brain, kidney and pancreas. Abundant in the cerebral cortex and expressed at much lower levels in the spinal cord. Not detected in the lymphoid tissues.