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Ran Polyclonal Antibody
商品货号: PLA017847
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: RAN
  • 蛋白名称: GTP-binding nuclear protein Ran
  • Human_gene_id: 5901
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5901
  • Human_swiss_prot_no: P62826
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P62826/entry
  • Mouse_gene_id: 1.00046e+008
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100045999
  • Mouse_swiss_prot_no: P62827
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P62827
  • Rat_gene_id: 84509
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84509
  • Rat_swiss_prot_no: P62828
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P62828
  • 特异性: Ran Polyclonal Antibody detects endogenous levels of Ran protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RAN; ARA24; OK/SW-cl.81; GTP-binding nuclear protein Ran; Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein
  • 实测条带: 25kD
  • 功能: function:Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.,function:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.,PTM:The N-terminus is blocked.,similarity:Belongs to the small GTPase superfamily. Ran family.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Monomer. Also forms a complex with CHC1 and interacts with the AR N-terminal poly-Gln region. The interaction with AR is inversely correlated with the poly-Gln length. Part of a complex consisting of RANBP9, Ran, DYRK1B and COPS5. Found in a nuclear export complex with RANBP3 and XPO1. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts with RANBP10. In case of HIV-1 infection, found in a complex with HIV-1 Rev, RNAs containing a Rev response element (RRE) and XPO1. Found in a complex with HTLV-1 Rex, RANBP3 and XPO1.,tissue specificity:Expressed in a variety of tissues.,
  • 相关产品: YT3998,KA3367C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Nucleus envelope . Cytoplasm, cytosol . Cytoplasm . Melanosome . Predominantly nuclear during interphase (PubMed:8421051, PubMed:12194828, PubMed:10679025). Becomes dispersed throughout the cytoplasm during mitosis (PubMed:8421051, PubMed:12194828). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
  • 组织表达: Expressed in a variety of tissues.
  • 科研货号: PLA017847
Ran Polyclonal Antibody
Catalog No PLA017847
Product information
  • 基因名称: RAN
  • 蛋白名称: GTP-binding nuclear protein Ran
  • Human_gene_id: 5901
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5901
  • Human_swiss_prot_no: P62826
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P62826/entry
  • Mouse_gene_id: 1.00046e+008
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=100045999
  • Mouse_swiss_prot_no: P62827
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P62827
  • Rat_gene_id: 84509
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=84509
  • Rat_swiss_prot_no: P62828
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P62828
  • 特异性: Ran Polyclonal Antibody detects endogenous levels of Ran protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: RAN; ARA24; OK/SW-cl.81; GTP-binding nuclear protein Ran; Androgen receptor-associated protein 24; GTPase Ran; Ras-like protein TC4; Ras-related nuclear protein
  • 实测条带: 25kD
  • 功能: function:Enhances AR-mediated transactivation. Transactivation decreases as the poly-Gln length within AR increases.,function:GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle.,PTM:The N-terminus is blocked.,similarity:Belongs to the small GTPase superfamily. Ran family.,subcellular location:Becomes dispersed throughout the cytoplasm during mitosis. Identified by mass spectrometry in melanosome fractions from stage I to stage IV.,subunit:Monomer. Also forms a complex with CHC1 and interacts with the AR N-terminal poly-Gln region. The interaction with AR is inversely correlated with the poly-Gln length. Part of a complex consisting of RANBP9, Ran, DYRK1B and COPS5. Found in a nuclear export complex with RANBP3 and XPO1. Component of a nuclear export receptor complex composed of KPNB1, Ran, SNUPN and XPO1. Found in a trimeric export complex with SNUPN, Ran and XPO1. Interacts with RANBP10. In case of HIV-1 infection, found in a complex with HIV-1 Rev, RNAs containing a Rev response element (RRE) and XPO1. Found in a complex with HTLV-1 Rex, RANBP3 and XPO1.,tissue specificity:Expressed in a variety of tissues.,
  • 相关产品: YT3998,KA3367C,RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus . Nucleus envelope . Cytoplasm, cytosol . Cytoplasm . Melanosome . Predominantly nuclear during interphase (PubMed:8421051, PubMed:12194828, PubMed:10679025). Becomes dispersed throughout the cytoplasm during mitosis (PubMed:8421051, PubMed:12194828). Identified by mass spectrometry in melanosome fractions from stage I to stage IV (PubMed:17081065). .
  • 组织表达: Expressed in a variety of tissues.
  • 科研货号: PLA017847
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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