其他名称： RAD54L; RAD54A; DNA repair and recombination protein RAD54-like; RAD54 homolog; hHR54; hRAD54
实测条带： 85kD
信号通路： Homologous recombination;
功能： disease:Defects in RAD54L may be a cause of tumor formation. Although alterations are found in a small fraction of primary tumors, these findings provide new insight into genetic instability underlying carcinogenesis.,function:Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.,induction:Expression increases approximately 3-fold in late G1 phase compared to other phases of the cell cycle.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus .
组织表达： Testis,Thymus,
科研货号： PLA017832
Rad54 Polyclonal Antibody
Catalog NoPLA017832
Product information
基因名称： RAD54L
蛋白名称： DNA repair and recombination protein RAD54-like
其他名称： RAD54L; RAD54A; DNA repair and recombination protein RAD54-like; RAD54 homolog; hHR54; hRAD54
实测条带： 85kD
信号通路： Homologous recombination;
功能： disease:Defects in RAD54L may be a cause of tumor formation. Although alterations are found in a small fraction of primary tumors, these findings provide new insight into genetic instability underlying carcinogenesis.,function:Involved in DNA repair and mitotic recombination. Functions in the recombinational DNA repair (RAD52) pathway. Dissociates RAD51 from nucleoprotein filaments formed on dsDNA. Could be involved in the turnover of RAD51 protein-dsDNA filaments (By similarity). May play also an essential role in telomere length maintenance and telomere capping in mammalian cells.,induction:Expression increases approximately 3-fold in late G1 phase compared to other phases of the cell cycle.,similarity:Belongs to the SNF2/RAD54 helicase family.,similarity:Contains 1 helicase ATP-binding domain.,similarity:Contains 1 helicase C-terminal domain.,subunit:Interacts with RAD51 through the NH2-terminal domain.,
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