Rab 3 GAP p130 Polyclonal Antibody

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商品货号： PLA017791

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： RAB3GAP1
蛋白名称： Rab3 GTPase-activating protein catalytic subunit
Human_gene_id： 22930
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22930
Human_swiss_prot_no： Q15042
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q15042/entry
Mouse_swiss_prot_no： Q80UJ7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q80UJ7
特异性： Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP
实测条带： 117kD
功能： disease:Defects in RAB3GAP1 are the cause of Warburg micro syndrome 1 (WARBM1) [MIM:600118]. WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia.,function:Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.,similarity:Belongs to the Rab3-GAP catalytic subunit family.,subcellular location:In neurons, it is enriched in the synaptic soluble fraction.,subunit:The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.
组织表达： Ubiquitous.
科研货号： PLA017791

Rab 3 GAP p130 Polyclonal Antibody

Catalog No PLA017791

Product information

基因名称： RAB3GAP1
蛋白名称： Rab3 GTPase-activating protein catalytic subunit
Human_gene_id： 22930
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=22930
Human_swiss_prot_no： Q15042
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q15042/entry
Mouse_swiss_prot_no： Q80UJ7
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q80UJ7
特异性： Rab 3 GAP p130 Polyclonal Antibody detects endogenous levels of Rab 3 GAP p130 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： RAB3GAP1; KIAA0066; RAB3GAP; Rab3 GTPase-activating protein catalytic subunit; RAB3 GTPase-activating protein 130 kDa subunit; Rab3-GAP p130; Rab3-GAP
实测条带： 117kD
功能： disease:Defects in RAB3GAP1 are the cause of Warburg micro syndrome 1 (WARBM1) [MIM:600118]. WARBM1 is a severe autosomal recessive disorder characterized by developmental abnormalities of the eye and central nervous system and by microgenitalia.,function:Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D). Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.,similarity:Belongs to the Rab3-GAP catalytic subunit family.,subcellular location:In neurons, it is enriched in the synaptic soluble fraction.,subunit:The Rab3 GTPase-activating complex is a heterodimer composed of RAB3GAP and RAB3-GAP150. The Rab3 GTPase-activating complex interacts with DMXL2.,tissue specificity:Ubiquitous.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . In neurons, it is enriched in the synaptic soluble fraction.
组织表达： Ubiquitous.
科研货号： PLA017791

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