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PTP1B Polyclonal Antibody
商品货号: PLA017769
适 应 性: 人,小鼠,大鼠,猴
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: PTPN1
  • 蛋白名称: Tyrosine-protein phosphatase non-receptor type 1
  • Human_gene_id: 5770
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5770
  • Human_swiss_prot_no: P18031
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P18031/entry
  • Mouse_gene_id: 19246
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19246
  • Mouse_swiss_prot_no: P35821
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P35821
  • Rat_gene_id: 24697
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24697
  • Rat_swiss_prot_no: P20417
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P20417
  • 特异性: PTP1B Polyclonal Antibody detects endogenous levels of PTP1B protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B
  • 实测条带: 49kD
  • 信号通路: Adherens_Junction;Insulin_Receptor;
  • 功能: catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:May play an important role in CKII- and p60c-src-induced signal transduction cascades.,PTM:Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the alpha-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
  • 相关产品: YT3900,YP0722,KA4257C,KA1416C
  • 细胞定位: Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Interacts with EPHA3 at the cell membrane.
  • 组织表达: Expressed in keratinocytes (at protein level).
  • 科研货号: PLA017769
PTP1B Polyclonal Antibody
Catalog No PLA017769
Product information
  • 基因名称: PTPN1
  • 蛋白名称: Tyrosine-protein phosphatase non-receptor type 1
  • Human_gene_id: 5770
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5770
  • Human_swiss_prot_no: P18031
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P18031/entry
  • Mouse_gene_id: 19246
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=19246
  • Mouse_swiss_prot_no: P35821
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P35821
  • Rat_gene_id: 24697
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24697
  • Rat_swiss_prot_no: P20417
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P20417
  • 特异性: PTP1B Polyclonal Antibody detects endogenous levels of PTP1B protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PTPN1; PTP1B; Tyrosine-protein phosphatase non-receptor type 1; Protein-tyrosine phosphatase 1B; PTP-1B
  • 实测条带: 49kD
  • 信号通路: Adherens_Junction;Insulin_Receptor;
  • 功能: catalytic activity:Protein tyrosine phosphate + H(2)O = protein tyrosine + phosphate.,function:May play an important role in CKII- and p60c-src-induced signal transduction cascades.,PTM:Oxidized on Cys-215; the Cys-SOH formed in response to redox signaling reacts with the alpha-amido of the following residue to form a 4-amino-3-isothiazolidinone serine cross-link, triggering a conformational change that inhibits substrate binding and activity. The active site can be restored by reduction.,similarity:Belongs to the protein-tyrosine phosphatase family. Non-receptor class 1 subfamily.,similarity:Contains 1 tyrosine-protein phosphatase domain.,
  • 相关产品: YT3900,YP0722,KA4257C,KA1416C
  • 细胞定位: Endoplasmic reticulum membrane ; Peripheral membrane protein ; Cytoplasmic side . Interacts with EPHA3 at the cell membrane.
  • 组织表达: Expressed in keratinocytes (at protein level).
  • 科研货号: PLA017769
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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