功能: function:The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.,PTM:Sumoylated by UBE2I in response to MEKK1-mediated stimuli.,similarity:Belongs to the AAA ATPase family.,subunit:May form a heterodimer with a related family member. Interacts with PAAF1. Interacts with HIV-1 Tat.,
相关产品: YT3884,KA4255C,RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus . Colocalizes with TRIM5 in the cytoplasmic bodies. .
功能: function:The 26S protease is involved in the ATP-dependent degradation of ubiquitinated proteins. The regulatory (or ATPase) complex confers ATP dependency and substrate specificity to the 26S complex (By similarity). In case of HIV-1 infection, suppresses Tat-mediated transactivation.,PTM:Sumoylated by UBE2I in response to MEKK1-mediated stimuli.,similarity:Belongs to the AAA ATPase family.,subunit:May form a heterodimer with a related family member. Interacts with PAAF1. Interacts with HIV-1 Tat.,
相关产品: YT3884,KA4255C,RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus . Colocalizes with TRIM5 in the cytoplasmic bodies. .