其他名称： DLG2; Disks large homolog 2; Channel-associated protein of synapse-110; Chapsyn-110; Postsynaptic density protein PSD-93
实测条带： 97kD
功能： domain:Isoform 2 has an L27 domain close to N-terminus.,function:Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.,PTM:Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.,similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 3 PDZ (DHR) domains.,subcellular location:Concentrated in soma and postsynaptic density of a subset of neurons.,subunit:Interacts with NOS1/nNOS through second PDZ domain (By similarity). Interacts with C-terminus of KCNJ2/Kir2.1 through one of its PDZ domains.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Membrane . Cell projection, axon . Perikaryon . Concentrated in soma and postsynaptic density of a subset of neurons. .
其他名称： DLG2; Disks large homolog 2; Channel-associated protein of synapse-110; Chapsyn-110; Postsynaptic density protein PSD-93
实测条带： 97kD
功能： domain:Isoform 2 has an L27 domain close to N-terminus.,function:Required for perception of chronic pain through NMDA receptor signaling. Regulates surface expression of NMDA receptors in dorsal horn neurons of the spinal cord. Interacts with the cytoplasmic tail of NMDA receptor subunits as well as inward rectifying potassium channels. Involved in regulation of synaptic stability at cholinergic synapses. Part of the postsynaptic protein scaffold of excitatory synapses.,PTM:Palmitoylation of isoform 1 is not required for targeting to postsynaptic density.,similarity:Belongs to the MAGUK family.,similarity:Contains 1 guanylate kinase-like domain.,similarity:Contains 1 SH3 domain.,similarity:Contains 3 PDZ (DHR) domains.,subcellular location:Concentrated in soma and postsynaptic density of a subset of neurons.,subunit:Interacts with NOS1/nNOS through second PDZ domain (By similarity). Interacts with C-terminus of KCNJ2/Kir2.1 through one of its PDZ domains.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor . Cell junction, synapse, postsynaptic density . Cell junction, synapse . Membrane . Cell projection, axon . Perikaryon . Concentrated in soma and postsynaptic density of a subset of neurons. .
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