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PRX II Polyclonal Antibody
商品货号: PLA017746
适 应 性: 人,小鼠,大鼠
WB IHC
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: PRDX2
  • 蛋白名称: Peroxiredoxin-2
  • Human_gene_id: 7001
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7001
  • Human_swiss_prot_no: P32119
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P32119/entry
  • Mouse_gene_id: 21672
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21672
  • Mouse_swiss_prot_no: Q61171
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q61171
  • Rat_gene_id: 29338
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29338
  • Rat_swiss_prot_no: P35704
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P35704
  • 特异性: PRX II Polyclonal Antibody detects endogenous levels of PRX II protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
  • 实测条带: 21kD
  • 功能: catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,function:Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).,miscellaneous:Inactivated upon oxidative stress by overoxidation of Cys-51 to Cys-SO(2)H and Cys-SO(3)H. Cys-SO(2)H is retroreduced to Cys-SOH after removal of H(2)O(2), while Cys-SO(3)H may be irreversibly oxidized.,miscellaneous:The active site is the redox-active Cys-51 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-172-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.,similarity:Belongs to the ahpC/TSA family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration. Interacts with TIPIN.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm .
  • 组织表达: Brain,Cajal-Retzius cell,Cerebellum,Colon carcinoma,Erythrocyte,Fetal brain cortex,Hypothal
  • 科研货号: PLA017746
PRX II Polyclonal Antibody
Catalog No PLA017746
Product information
  • 基因名称: PRDX2
  • 蛋白名称: Peroxiredoxin-2
  • Human_gene_id: 7001
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=7001
  • Human_swiss_prot_no: P32119
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P32119/entry
  • Mouse_gene_id: 21672
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=21672
  • Mouse_swiss_prot_no: Q61171
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q61171
  • Rat_gene_id: 29338
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29338
  • Rat_swiss_prot_no: P35704
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P35704
  • 特异性: PRX II Polyclonal Antibody detects endogenous levels of PRX II protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PRDX2; NKEFB; TDPX1; Peroxiredoxin-2; Natural killer cell-enhancing factor B; NKEF-B; PRP; Thiol-specific antioxidant protein; TSA; Thioredoxin peroxidase 1; Thioredoxin-dependent peroxide reductase 1
  • 实测条带: 21kD
  • 功能: catalytic activity:2 R'-SH + ROOH = R'-S-S-R' + H(2)O + ROH.,function:Involved in redox regulation of the cell. Reduces peroxides with reducing equivalents provided through the thioredoxin system. It is not able to receive electrons from glutaredoxin. May play an important role in eliminating peroxides generated during metabolism. Might participate in the signaling cascades of growth factors and tumor necrosis factor-alpha by regulating the intracellular concentrations of H(2)O(2).,miscellaneous:Inactivated upon oxidative stress by overoxidation of Cys-51 to Cys-SO(2)H and Cys-SO(3)H. Cys-SO(2)H is retroreduced to Cys-SOH after removal of H(2)O(2), while Cys-SO(3)H may be irreversibly oxidized.,miscellaneous:The active site is the redox-active Cys-51 oxidized to Cys-SOH. Cys-SOH rapidly reacts with Cys-172-SH of the other subunit to form an intermolecular disulfide with a concomitant homodimer formation. The enzyme may be subsequently regenerated by reduction of the disulfide by thioredoxin.,similarity:Belongs to the ahpC/TSA family.,similarity:Contains 1 thioredoxin domain.,subunit:Homodimer; disulfide-linked, upon oxidation. May be found as a toroid-shaped decamer composed of 5 dimers, depending on pH and calcium concentration. Interacts with TIPIN.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm .
  • 组织表达: Brain,Cajal-Retzius cell,Cerebellum,Colon carcinoma,Erythrocyte,Fetal brain cortex,Hypothal
  • 科研货号: PLA017746
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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