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PPP1R3A Polyclonal Antibody
商品货号: PLA017719
适 应 性: 人,大鼠,小鼠,
WB IHC
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: PPP1R3A
  • 蛋白名称: Protein phosphatase 1 regulatory subunit 3A
  • Human_gene_id: 5506
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5506
  • Human_swiss_prot_no: Q16821
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q16821/entry
  • Mouse_swiss_prot_no: Q99MR9
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q99MR9
  • 特异性: PPP1R3A Polyclonal Antibody detects endogenous levels of PPP1R3A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PPP1R3A; PP1G; Protein phosphatase 1 regulatory subunit 3A; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase type-1 glycogen targeting subunit; RG1
  • 实测条带: 140kD
  • 信号通路: Insulin_Receptor;
  • 功能: disease:Defects in PPP1R3A are a cause of insulin resistance (Ins resistance).,disease:Defects in PPP1R3A are a cause of susceptibility to noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type II. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.,domain:The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.,function:Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.,PTM:Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.,similarity:Contains 1 CBM21 (carbohydrate binding type-21) domain.,subunit:Interacts with PPP1CC catalytic subunit of PP1, and associates with glycogen.,tissue specificity:Skeletal muscle and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane ; Single-pass membrane protein .
  • 组织表达: Skeletal muscle and heart.
  • 科研货号: PLA017719
PPP1R3A Polyclonal Antibody
Catalog No PLA017719
Product information
  • 基因名称: PPP1R3A
  • 蛋白名称: Protein phosphatase 1 regulatory subunit 3A
  • Human_gene_id: 5506
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5506
  • Human_swiss_prot_no: Q16821
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q16821/entry
  • Mouse_swiss_prot_no: Q99MR9
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q99MR9
  • 特异性: PPP1R3A Polyclonal Antibody detects endogenous levels of PPP1R3A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PPP1R3A; PP1G; Protein phosphatase 1 regulatory subunit 3A; Protein phosphatase 1 glycogen-associated regulatory subunit; Protein phosphatase type-1 glycogen targeting subunit; RG1
  • 实测条带: 140kD
  • 信号通路: Insulin_Receptor;
  • 功能: disease:Defects in PPP1R3A are a cause of insulin resistance (Ins resistance).,disease:Defects in PPP1R3A are a cause of susceptibility to noninsulin-dependent diabetes mellitus (NIDDM) [MIM:125853]; also known as diabetes mellitus type II. NIDDM is characterized by an autosomal dominant mode of inheritance, onset during adulthood and insulin resistance.,domain:The CBM21 domain is known to be involved in the localization to glycogen and is characteristic of some regulatory subunit of phosphatase complexes.,function:Seems to act as a glycogen-targeting subunit for PP1. PP1 is essential for cell division, and participates in the regulation of glycogen metabolism, muscle contractility and protein synthesis. Plays an important role in glycogen synthesis but is not essential for insulin activation of glycogen synthase.,PTM:Phosphorylation at Ser-46 by ISPK stimulates the dephosphorylation of glycogen synthase and phosphorylase kinase.,similarity:Contains 1 CBM21 (carbohydrate binding type-21) domain.,subunit:Interacts with PPP1CC catalytic subunit of PP1, and associates with glycogen.,tissue specificity:Skeletal muscle and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Membrane ; Single-pass membrane protein .
  • 组织表达: Skeletal muscle and heart.
  • 科研货号: PLA017719
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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