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PP4R2 Polyclonal Antibody
商品货号: PLA017713
适 应 性: 人,猴
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: PPP4R2
  • 蛋白名称: Serine/threonine-protein phosphatase 4 regulatory subunit 2
  • Human_gene_id: 151987
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=151987
  • Human_swiss_prot_no: Q9NY27
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9NY27/entry
  • Mouse_swiss_prot_no: Q0VGB7
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q0VGB7
  • 特异性: PP4R2 Polyclonal Antibody detects endogenous levels of PP4R2 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2
  • 实测条带: 50kD
  • 功能: function:Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PPP4R2 family.,subunit:Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complexes PPP4C-PPP4R2, PPP4C-PPP4R2-PPP4R3A and PPP4C-PPP4R2-PPP4R3B. The PPP4C-PPP4R2 complex appears to be a tetramer composed of 2 molecules of PPP4C and 2 molecules of PPP4R2. Interacts with DDX20/GEMIN3 and GEMIN4.,tissue specificity:Widely expressed.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.
  • 组织表达: Widely expressed.
  • 科研货号: PLA017713
PP4R2 Polyclonal Antibody
Catalog No PLA017713
Product information
  • 基因名称: PPP4R2
  • 蛋白名称: Serine/threonine-protein phosphatase 4 regulatory subunit 2
  • Human_gene_id: 151987
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=151987
  • Human_swiss_prot_no: Q9NY27
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q9NY27/entry
  • Mouse_swiss_prot_no: Q0VGB7
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q0VGB7
  • 特异性: PP4R2 Polyclonal Antibody detects endogenous levels of PP4R2 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PPP4R2; SBBI57; Serine/threonine-protein phosphatase 4 regulatory subunit 2
  • 实测条带: 50kD
  • 功能: function:Regulatory subunit of serine/threonine-protein phosphatase 4 (PP4). May regulate the activity of PPP4C at centrosomal microtubule organizing centers. Its interaction with the SMN complex leads to enhance the temporal localization of snRNPs, suggesting a role of PPP4C in maturation of spliceosomal snRNPs. The PPP4C-PPP4R2-PPP4R3A PP4 complex specifically dephosphorylates H2AFX phosphorylated on 'Ser-140' (gamma-H2AFX) generated during DNA replication and required for DNA DSB repair.,sequence caution:Contaminating sequence. Potential poly-A sequence.,similarity:Belongs to the PPP4R2 family.,subunit:Serine/threonine-protein phosphatase 4 (PP4) occurs in different assemblies of the catalytic and one or more regulatory subunits. Component of the PP4 complexes PPP4C-PPP4R2, PPP4C-PPP4R2-PPP4R3A and PPP4C-PPP4R2-PPP4R3B. The PPP4C-PPP4R2 complex appears to be a tetramer composed of 2 molecules of PPP4C and 2 molecules of PPP4R2. Interacts with DDX20/GEMIN3 and GEMIN4.,tissue specificity:Widely expressed.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Nucleus. Ionizing radiation induces relocalization to nuclear foci and colocalization with RPA2.
  • 组织表达: Widely expressed.
  • 科研货号: PLA017713
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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