其他名称: PPP2R5D; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta
实测条带: 70kD
信号通路: Oocyte meiosis;WNT;WNT-T CELL
功能: function:The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.,induction:By retinoic acid; in neuroblastoma cell lines.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase 2A regulatory subunit B56 family.,subcellular location:Nuclear in interphase, nuclear during mitosis.,subunit:PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGOL1.,tissue specificity:Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm. Nucleus. Nuclear in interphase, nuclear during mitosis.
组织表达: Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.
其他名称: PPP2R5D; Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit delta isoform; PP2A B subunit isoform B'-delta; PP2A B subunit isoform B56-delta; PP2A B subunit isoform PR61-delta; PP2A B subunit isoform R5-delta
实测条带: 70kD
信号通路: Oocyte meiosis;WNT;WNT-T CELL
功能: function:The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.,induction:By retinoic acid; in neuroblastoma cell lines.,PTM:Phosphorylated upon DNA damage, probably by ATM or ATR.,similarity:Belongs to the phosphatase 2A regulatory subunit B56 family.,subcellular location:Nuclear in interphase, nuclear during mitosis.,subunit:PP2A consists of a common heterodimeric core enzyme, composed of a 36 kDa catalytic subunit (subunit C) and a 65 kDa constant regulatory subunit (PR65 or subunit A), that associates with a variety of regulatory subunits. Proteins that associate with the core dimer include three families of regulatory subunits B (the R2/B/PR55/B55, R3/B''/PR72/PR130/PR59 and R5/B'/B56 families), the 48 kDa variable regulatory subunit, viral proteins, and cell signaling molecules. Interacts with SGOL1.,tissue specificity:Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm. Nucleus. Nuclear in interphase, nuclear during mitosis.
组织表达: Isoform Delta-2 is widely expressed. Isoform Delta-1 is highly expressed in brain.