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POLR3A Polyclonal Antibody
商品货号: PLA017692
适 应 性: 人,小鼠,猴
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: POLR3A
  • 蛋白名称: DNA-directed RNA polymerase III subunit RPC1
  • Human_gene_id: 11128
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11128
  • Human_swiss_prot_no: O14802
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O14802/entry
  • 特异性: POLR3A Polyclonal Antibody detects endogenous levels of POLR3A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: POLR3A; DNA-directed RNA polymerase III subunit RPC1; RNA polymerase III subunit C1; DNA-directed RNA polymerase III largest subunit; DNA-directed RNA polymerase III subunit A; RNA polymerase III 155 kDa subunit; RPC155; RNA polymerase III
  • 实测条带: 156kD
  • 信号通路: Purine metabolism;Pyrimidine metabolism;RNA polymerase;Cytosolic DNA-sensing pathway;
  • 功能: catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.,similarity:Belongs to the RNA polymerase beta' chain family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus.
  • 组织表达: Expressed in the brain, in the cortex and the white matter (at protein level).
  • 科研货号: PLA017692
POLR3A Polyclonal Antibody
Catalog No PLA017692
Product information
  • 基因名称: POLR3A
  • 蛋白名称: DNA-directed RNA polymerase III subunit RPC1
  • Human_gene_id: 11128
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=11128
  • Human_swiss_prot_no: O14802
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/O14802/entry
  • 特异性: POLR3A Polyclonal Antibody detects endogenous levels of POLR3A protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: POLR3A; DNA-directed RNA polymerase III subunit RPC1; RNA polymerase III subunit C1; DNA-directed RNA polymerase III largest subunit; DNA-directed RNA polymerase III subunit A; RNA polymerase III 155 kDa subunit; RPC155; RNA polymerase III
  • 实测条带: 156kD
  • 信号通路: Purine metabolism;Pyrimidine metabolism;RNA polymerase;Cytosolic DNA-sensing pathway;
  • 功能: catalytic activity:Nucleoside triphosphate + RNA(n) = diphosphate + RNA(n+1).,function:DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. Largest and catalytic core component of RNA polymerase III which synthesizes small RNAs, such as 5S rRNA and tRNAs. Forms the polymerase active center together with the second largest subunit. A single stranded DNA template strand of the promoter is positioned within the central active site cleft of Pol III. A bridging helix emanates from RPC1 and crosses the cleft near the catalytic site and is thought to promote translocation of Pol III by acting as a ratchet that moves the RNA-DNA hybrid through the active site by switching from straight to bent conformations at each step of nucleotide addition.,similarity:Belongs to the RNA polymerase beta' chain family.,subunit:Component of the RNA polymerase III (Pol III) complex consisting of 17 subunits.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Nucleus.
  • 组织表达: Expressed in the brain, in the cortex and the white matter (at protein level).
  • 科研货号: PLA017692
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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