其他名称: PKIA; PRKACN1; cAMP-dependent protein kinase inhibitor alpha; PKI-alpha; cAMP-dependent protein kinase inhibitor; muscle/brain isoform
分子量: 8kD
功能: function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,miscellaneous:The inhibitory site contains regions very similar to the hinge regions (sites that directly interact with the enzyme active site) and "pseudosubstrate site" of the regulatory chains; but, unlike these chains, PKI does not contain cAMP-binding sites. The arginine residues within the inhibitory site are essential for inhibition and recognition of the enzyme active site.,similarity:Belongs to the PKI family.,
相关产品: YT3775,KA3656C,RS0001,RS0002,YM3028,YM3029
细胞定位: nucleus,cytoplasm,
组织表达: Skeletal muscle,
科研货号: PLA017660
Pki α Polyclonal Antibody
Catalog NoPLA017660
Product information
基因名称: PKIA
蛋白名称: cAMP-dependent protein kinase inhibitor alpha
其他名称: PKIA; PRKACN1; cAMP-dependent protein kinase inhibitor alpha; PKI-alpha; cAMP-dependent protein kinase inhibitor; muscle/brain isoform
分子量: 8kD
功能: function:Extremely potent competitive inhibitor of cAMP-dependent protein kinase activity, this protein interacts with the catalytic subunit of the enzyme after the cAMP-induced dissociation of its regulatory chains.,miscellaneous:The inhibitory site contains regions very similar to the hinge regions (sites that directly interact with the enzyme active site) and "pseudosubstrate site" of the regulatory chains; but, unlike these chains, PKI does not contain cAMP-binding sites. The arginine residues within the inhibitory site are essential for inhibition and recognition of the enzyme active site.,similarity:Belongs to the PKI family.,