首页 > 抗体 > 一抗 > 其它 > PKC ζ Polyclonal Antibody
PKC ζ Polyclonal Antibody
商品货号: PLA017654
适 应 性: 人,小鼠,大鼠,猴
WB IHC IF ELISA
¥600元
规格:
在线咨询
MSDS
说明书
商品描述
  • 基因名称: PRKCZ
  • 蛋白名称: Protein kinase C zeta type
  • Human_gene_id: 5590
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5590
  • Human_swiss_prot_no: Q05513
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05513/entry
  • Mouse_gene_id: 18762
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18762
  • Mouse_swiss_prot_no: Q02956
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q02956
  • Rat_gene_id: 25522
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25522
  • Rat_swiss_prot_no: P09217
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P09217
  • 特异性: PKC ζ Polyclonal Antibody detects endogenous levels of PKC ζ protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta
  • 实测条带: 80kD
  • 信号通路: Regulation_Microtubule; Regulation of Actin Dynamics; Stem cell pathway; Insulin Receptor; PI3K/Akt; B Cell Receptor; AMPK
  • 功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,domain:The OPR domain mediates mutually exclusive interactions with SQSTM1 and PARD6B.,enzyme regulation:Phosphatidylinositol 3,4,5-trisphosphate might be a physiological activator. Two specific sites, Thr-410 (activation loop of the kinase domain) and Thr-560 (turn motif), need to be phosphorylated for its full activation.,function:PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.,function:This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 OPR domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subcellular location:In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes.,subunit:Forms a ternary complex with SQSTM1 and KCNAB2. Forms another ternary complex with SQSTM1 and GABRR3. Forms a complex with SQSTM1 and MAP2K5 (By similarity). Interacts with PARD6A, PARD6B, PARD6G and SQSTM1. Part of a complex with PARD3, PARD6A or PARD6B or PARD6G and CDC42 or RAC1. Interacts with ADAP1/CENTA1. Forms a ternary complex composed of SQSTM1 and PAWR. Interacts directly with SQSTM1 (Probable). Interacts with IKBKB.,tissue specificity:Expressed in brain, and to a lesser extent in lung, kidney and testis.,
  • 相关产品: YT3765,YT3764,YP0230,YP0229,KA4239C,KA1412C,KA1177C
  • 细胞定位: Cytoplasm . Endosome . Cell junction . Membrane ; Peripheral membrane protein . In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes (PubMed:9566925). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction (PubMed:7597083). Colocalizes with VAMP2 and WDFY2 in intracellular vesicles (PubMed:17313651). Transiently translocates to the membrane of CA1 hippocampal cells in response to the induction of long term potentiation (By similarity). .; [Isoform 2]: Cytoplasm .
  • 组织表达: Expressed in brain, and to a lesser extent in lung, kidney and testis.
  • tag: hot
  • 科研货号: PLA017654
PKC ζ Polyclonal Antibody
Catalog No PLA017654
Product information
  • 基因名称: PRKCZ
  • 蛋白名称: Protein kinase C zeta type
  • Human_gene_id: 5590
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=5590
  • Human_swiss_prot_no: Q05513
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q05513/entry
  • Mouse_gene_id: 18762
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18762
  • Mouse_swiss_prot_no: Q02956
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q02956
  • Rat_gene_id: 25522
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25522
  • Rat_swiss_prot_no: P09217
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P09217
  • 特异性: PKC ζ Polyclonal Antibody detects endogenous levels of PKC ζ protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: PRKCZ; PKC2; Protein kinase C zeta type; nPKC-zeta
  • 实测条带: 80kD
  • 信号通路: Regulation_Microtubule; Regulation of Actin Dynamics; Stem cell pathway; Insulin Receptor; PI3K/Akt; B Cell Receptor; AMPK
  • 功能: catalytic activity:ATP + a protein = ADP + a phosphoprotein.,domain:The C1 domain does not bind the diacylglycerol (DAG).,domain:The OPR domain mediates mutually exclusive interactions with SQSTM1 and PARD6B.,enzyme regulation:Phosphatidylinositol 3,4,5-trisphosphate might be a physiological activator. Two specific sites, Thr-410 (activation loop of the kinase domain) and Thr-560 (turn motif), need to be phosphorylated for its full activation.,function:PKC is activated by diacylglycerol which in turn phosphorylates a range of cellular proteins. PKC also serves as the receptor for phorbol esters, a class of tumor promoters. Subunit of a quaternary complex that plays a central role in epithelial cell polarization.,function:This is a calcium-independent, phospholipid-dependent, serine- and threonine-specific enzyme.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily.,similarity:Contains 1 AGC-kinase C-terminal domain.,similarity:Contains 1 OPR domain.,similarity:Contains 1 phorbol-ester/DAG-type zinc finger.,similarity:Contains 1 protein kinase domain.,subcellular location:In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes.,subunit:Forms a ternary complex with SQSTM1 and KCNAB2. Forms another ternary complex with SQSTM1 and GABRR3. Forms a complex with SQSTM1 and MAP2K5 (By similarity). Interacts with PARD6A, PARD6B, PARD6G and SQSTM1. Part of a complex with PARD3, PARD6A or PARD6B or PARD6G and CDC42 or RAC1. Interacts with ADAP1/CENTA1. Forms a ternary complex composed of SQSTM1 and PAWR. Interacts directly with SQSTM1 (Probable). Interacts with IKBKB.,tissue specificity:Expressed in brain, and to a lesser extent in lung, kidney and testis.,
  • 相关产品: YT3765,YT3764,YP0230,YP0229,KA4239C,KA1412C,KA1177C
  • 细胞定位: Cytoplasm . Endosome . Cell junction . Membrane ; Peripheral membrane protein . In the retina, localizes in the terminals of the rod bipolar cells (By similarity). Associates with endosomes (PubMed:9566925). Presence of KRIT1, CDH5 and RAP1B is required for its localization to the cell junction (PubMed:7597083). Colocalizes with VAMP2 and WDFY2 in intracellular vesicles (PubMed:17313651). Transiently translocates to the membrane of CA1 hippocampal cells in response to the induction of long term potentiation (By similarity). .; [Isoform 2]: Cytoplasm .
  • 组织表达: Expressed in brain, and to a lesser extent in lung, kidney and testis.
  • tag: hot
  • 科研货号: PLA017654
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
普拉特泽实验室电话助手

4006916686

扫码咨询