PDZ-RhoGEF Polyclonal Antibody

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商品货号： PLA017556

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： ARHGEF11
蛋白名称： Rho guanine nucleotide exchange factor 11
Human_gene_id： 9826
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9826
Human_swiss_prot_no： O15085
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15085/entry
Rat_gene_id： 78966
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78966
Rat_swiss_prot_no： Q9ES67
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9ES67
特异性： PDZ-RhoGEF Polyclonal Antibody detects endogenous levels of PDZ-RhoGEF protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF
分子量： 168kD
信号通路： Regulation of Actin Dynamics; AMPK
功能： domain:The poly-Pro region is essential for plasma membrane localization upon stimulation.,function:May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 RGSL (RGS-like) domain.,subcellular location:Translocated to the membrane upon stimulation.,subunit:Interacts with GNA12 and GNA13 through the RGS domain. Interacts with RHOA, PLXNB1 and PLXNB2. Interacts with SLC1A6.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Membrane . Translocated to the membrane upon stimulation.
组织表达： Ubiquitously expressed.
科研货号： PLA017556

PDZ-RhoGEF Polyclonal Antibody

Catalog No PLA017556

Product information

基因名称： ARHGEF11
蛋白名称： Rho guanine nucleotide exchange factor 11
Human_gene_id： 9826
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9826
Human_swiss_prot_no： O15085
Human_swiss_link： http://www.uniprot.org/uniprotkb/O15085/entry
Rat_gene_id： 78966
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=78966
Rat_swiss_prot_no： Q9ES67
Rat_swiss_link： http://www.uniprot.org/uniprot/Q9ES67
特异性： PDZ-RhoGEF Polyclonal Antibody detects endogenous levels of PDZ-RhoGEF protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500-2000;IHC-p 1:50-300
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： ARHGEF11; KIAA0380; Rho guanine nucleotide exchange factor 11; PDZ-RhoGEF
分子量： 168kD
信号通路： Regulation of Actin Dynamics; AMPK
功能： domain:The poly-Pro region is essential for plasma membrane localization upon stimulation.,function:May play a role in the regulation of RhoA GTPase by guanine nucleotide-binding alpha-12 (GNA12) and alpha-13 (GNA13). Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase and may act as GTPase-activating protein (GAP) for GNA12 and GNA13.,similarity:Contains 1 DH (DBL-homology) domain.,similarity:Contains 1 PDZ (DHR) domain.,similarity:Contains 1 PH domain.,similarity:Contains 1 RGSL (RGS-like) domain.,subcellular location:Translocated to the membrane upon stimulation.,subunit:Interacts with GNA12 and GNA13 through the RGS domain. Interacts with RHOA, PLXNB1 and PLXNB2. Interacts with SLC1A6.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Membrane . Translocated to the membrane upon stimulation.
组织表达： Ubiquitously expressed.
科研货号： PLA017556

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