信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Cytokine-cytokine receptor interaction;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Glioma;Prostate cancer;Melanoma;
功能: domain:The long form contains a basic insert which acts as a cell retention signal.,function:Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.,miscellaneous:A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor.,similarity:Belongs to the PDGF/VEGF growth factor family.,subunit:Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted. Released by platelets upon wounding.
信号通路: MAPK_ERK_Growth;MAPK_G_Protein;Cytokine-cytokine receptor interaction;Focal adhesion;Gap junction;Regulates Actin and Cytoskeleton;Pathways in cancer;Glioma;Prostate cancer;Melanoma;
功能: domain:The long form contains a basic insert which acts as a cell retention signal.,function:Platelet-derived growth factor is a potent mitogen for cells of mesenchymal origin. Binding of this growth factor to its affinity receptor elicits a variety of cellular responses. It is released by platelets upon wounding and plays an important role in stimulating adjacent cells to grow and thereby heals the wound.,miscellaneous:A-A and B-B, as well as A-B, dimers can bind to the PDGF receptor.,similarity:Belongs to the PDGF/VEGF growth factor family.,subunit:Antiparallel disulfide-linked dimer of non-identical (A and B) chains. Homodimers of A and B chains are implicated in transformation processes. Interacts with CSPG4.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Secreted. Released by platelets upon wounding.