功能: catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,similarity:Contains 1 BRCT domain.,similarity:Contains 1 PARP alpha-helical domain.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 VWFA domain.,subcellular location:Also found in the nucleus, associated with mitotic spindles.,subunit:Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to MVP. Associates with TEP1.,tissue specificity:Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Also found in the nucleus, associated with mitotic spindles. .
组织表达: Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.
功能: catalytic activity:NAD(+) + (ADP-D-ribosyl)(n)-acceptor = nicotinamide + (ADP-D-ribosyl)(n+1)-acceptor.,similarity:Contains 1 BRCT domain.,similarity:Contains 1 PARP alpha-helical domain.,similarity:Contains 1 PARP catalytic domain.,similarity:Contains 1 VWFA domain.,subcellular location:Also found in the nucleus, associated with mitotic spindles.,subunit:Component of the vault ribonucleoprotein particle, at least composed of MVP, PARP4 and one or more vault RNAs (vRNAs). Binds to MVP. Associates with TEP1.,tissue specificity:Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cytoplasm . Nucleus . Cytoplasm, cytoskeleton, spindle . Also found in the nucleus, associated with mitotic spindles. .
组织表达: Widely expressed; the highest levels are in the kidney; also detected in heart, placenta, lung, liver, skeletal muscle, spleen, leukocytes and pancreas.