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p15 Polyclonal Antibody
商品货号: PLA017456
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: CDKN2B
  • 蛋白名称: Cyclin-dependent kinase 4 inhibitor B
  • Human_gene_id: 1030
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1030
  • Human_swiss_prot_no: P42772
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P42772/entry
  • Mouse_gene_id: 12579
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12579
  • Mouse_swiss_prot_no: P55271
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P55271
  • Rat_gene_id: 25164
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25164
  • Rat_swiss_prot_no: P55272
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P55272
  • 特异性: p15 Polyclonal Antibody detects endogenous levels of p15 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDKN2B; MTS2; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B
  • 实测条带: 14kD
  • 信号通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;TGF-beta;Pathways in cancer;Small cell lung cancer;
  • 功能: disease:Defects in CDKN2B are involved in tumor formation.,function:Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.,polymorphism:Genetic variations in CDKN2B may underlie susceptibility to uveal melanoma [MIM:155720]. Uveal melanoma is the most common type of ocular malignant tumor, consisting of overgrowth of uveal melanocytes and often preceded by a uveal nevus.,similarity:Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.,similarity:Contains 4 ANK repeats.,subunit:Heterodimer of CDKN2B with CDK4 or CDK6.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Also found in the nucleus.
  • 组织表达: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
  • 科研货号: PLA017456
p15 Polyclonal Antibody
Catalog No PLA017456
Product information
  • 基因名称: CDKN2B
  • 蛋白名称: Cyclin-dependent kinase 4 inhibitor B
  • Human_gene_id: 1030
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1030
  • Human_swiss_prot_no: P42772
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P42772/entry
  • Mouse_gene_id: 12579
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12579
  • Mouse_swiss_prot_no: P55271
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P55271
  • Rat_gene_id: 25164
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25164
  • Rat_swiss_prot_no: P55272
  • Rat_swiss_link: http://www.uniprot.org/uniprot/P55272
  • 特异性: p15 Polyclonal Antibody detects endogenous levels of p15 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDKN2B; MTS2; Cyclin-dependent kinase 4 inhibitor B; Multiple tumor suppressor 2; MTS-2; p14-INK4b; p15-INK4b; p15INK4B
  • 实测条带: 14kD
  • 信号通路: Cell_Cycle_G1S;Cell_Cycle_G2M_DNA;TGF-beta;Pathways in cancer;Small cell lung cancer;
  • 功能: disease:Defects in CDKN2B are involved in tumor formation.,function:Interacts strongly with CDK4 and CDK6. Potent inhibitor. Potential effector of TGF-beta induced cell cycle arrest.,polymorphism:Genetic variations in CDKN2B may underlie susceptibility to uveal melanoma [MIM:155720]. Uveal melanoma is the most common type of ocular malignant tumor, consisting of overgrowth of uveal melanocytes and often preceded by a uveal nevus.,similarity:Belongs to the CDKN2 cyclin-dependent kinase inhibitor family.,similarity:Contains 4 ANK repeats.,subunit:Heterodimer of CDKN2B with CDK4 or CDK6.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Also found in the nucleus.
  • 组织表达: Isoform 2 is expressed in normal (keratinocytes, fibroblasts) and tumor cell lines.
  • 科研货号: PLA017456
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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