其他名称： SLC22A18; BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; Solute carrier family 22 member 18; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Efflux transporter-like protein; Imprinted multi-membrane-spa
实测条带： 43kD
功能： caution:It is uncertain whether Met-1 or Met-17 is the initiator.,disease:Defects in SLC22A18 are associated with breast cancer [MIM:114480].,disease:Defects in SLC22A18 are associated with lung cancer [MIM:211980].,disease:Defects in SLC22A18 are the cause of rhabdomyosarcoma type 1 (RMS1) [MIM:268210]. Rhabdomyosarcoma is a malignant tumor (sarcoma) derived from striated muscle.,function:May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,subcellular location:Localized at the apical membrane surface of renal proximal tubules.,subunit:Interacts with RNF167.,tissue specificity:Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Apical cell membrane ; Multi-pass membrane protein . Localized at the apical membrane surface of renal proximal tubules. .
组织表达： Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.
其他名称： SLC22A18; BWR1A; BWSCR1A; HET; IMPT1; ITM; ORCTL2; SLC22A1L; TSSC5; Solute carrier family 22 member 18; Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene A protein; Efflux transporter-like protein; Imprinted multi-membrane-spa
实测条带： 43kD
功能： caution:It is uncertain whether Met-1 or Met-17 is the initiator.,disease:Defects in SLC22A18 are associated with breast cancer [MIM:114480].,disease:Defects in SLC22A18 are associated with lung cancer [MIM:211980].,disease:Defects in SLC22A18 are the cause of rhabdomyosarcoma type 1 (RMS1) [MIM:268210]. Rhabdomyosarcoma is a malignant tumor (sarcoma) derived from striated muscle.,function:May act as a transporter of organic cations based on a proton efflux antiport mechanism. May play a role in the transport of chloroquine and quinidine-related compounds in kidney.,similarity:Belongs to the major facilitator superfamily. Organic cation transporter family.,subcellular location:Localized at the apical membrane surface of renal proximal tubules.,subunit:Interacts with RNF167.,tissue specificity:Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Apical cell membrane ; Multi-pass membrane protein . Localized at the apical membrane surface of renal proximal tubules. .
组织表达： Expressed at high levels in adult and fetal kidney and liver, and adult colon. Expressed in fetal renal proximal tubules (at protein level). Expressed at lower levels in heart, brain and lung.
在线咨询
湘公网安备