NT5C3 Polyclonal Antibody

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商品货号： PLA017176

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NT5C3
蛋白名称： Cytosolic 5'-nucleotidase 3
Human_gene_id： 51251
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51251
Human_swiss_prot_no： Q9H0P0
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9H0P0/entry
Mouse_gene_id： 107569
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107569
Mouse_swiss_prot_no： Q9D020
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D020
特异性： NT5C3 Polyclonal Antibody detects endogenous levels of NT5C3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NT5C3; P5N1; UMPH1; HSPC233; Cytosolic 5'-nucleotidase 3; Cytosolic 5'-nucleotidase III; cN-III; Pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; Uridine 5'-monophosphate hydrolase 1; p36
实测条带： 38kD
信号通路： Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;
功能： catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,disease:Defects in NT5C3 are the cause of P5N deficiency [MIM:266120]; also called hemolytic anemia due to P5N deficiency or hemolytic anemia due to UMPH1 deficiency. P5N deficiency is an autosomal recessive condition causing hemolytic anemia characterized by marked basophilic stipplig and the accumulation of high concentrations of pyrimidine nucleotides within the erythrocyte. It is implicated in the anemia of lead poisoning and is possibly associated with learning difficulties.,function:Can act both as nucleotidase and as phosphotransferase.,induction:Isoform 2 is induced by interferon alpha in Raji cells in association with lupus inclusions.,similarity:Belongs to the pyrimidine 5'-nucleotidase family.,subunit:Monomer.,tissue specificity:Isoform 1 and isoform 3 are expressed in reticulocytes and lymphocytes. Isoform 4 is expressed only in reticulocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .; [Isoform 2]: Endoplasmic reticulum.
组织表达： Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver.
科研货号： PLA017176

NT5C3 Polyclonal Antibody

Catalog No PLA017176

Product information

基因名称： NT5C3
蛋白名称： Cytosolic 5'-nucleotidase 3
Human_gene_id： 51251
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=51251
Human_swiss_prot_no： Q9H0P0
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9H0P0/entry
Mouse_gene_id： 107569
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=107569
Mouse_swiss_prot_no： Q9D020
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D020
特异性： NT5C3 Polyclonal Antibody detects endogenous levels of NT5C3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:40000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NT5C3; P5N1; UMPH1; HSPC233; Cytosolic 5'-nucleotidase 3; Cytosolic 5'-nucleotidase III; cN-III; Pyrimidine 5'-nucleotidase 1; P5'N-1; P5N-1; PN-I; Uridine 5'-monophosphate hydrolase 1; p36
实测条带： 38kD
信号通路： Purine metabolism;Pyrimidine metabolism;Nicotinate and nicotinamide metabolism;
功能： catalytic activity:A 5'-ribonucleotide + H(2)O = a ribonucleoside + phosphate.,disease:Defects in NT5C3 are the cause of P5N deficiency [MIM:266120]; also called hemolytic anemia due to P5N deficiency or hemolytic anemia due to UMPH1 deficiency. P5N deficiency is an autosomal recessive condition causing hemolytic anemia characterized by marked basophilic stipplig and the accumulation of high concentrations of pyrimidine nucleotides within the erythrocyte. It is implicated in the anemia of lead poisoning and is possibly associated with learning difficulties.,function:Can act both as nucleotidase and as phosphotransferase.,induction:Isoform 2 is induced by interferon alpha in Raji cells in association with lupus inclusions.,similarity:Belongs to the pyrimidine 5'-nucleotidase family.,subunit:Monomer.,tissue specificity:Isoform 1 and isoform 3 are expressed in reticulocytes and lymphocytes. Isoform 4 is expressed only in reticulocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .; [Isoform 2]: Endoplasmic reticulum.
组织表达： Isoforms 1, 3 and 4 are expressed in reticulocytes. Isoform 4 is hardly detectable in bone marrow and fetal liver.
科研货号： PLA017176

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