其他名称: NOLC1; KIAA0035; NS5ATP13; Nucleolar and coiled-body phosphoprotein 1; 140 kDa nucleolar phosphoprotein; Nopp140; Hepatitis C virus NS5A-transactivated protein 13; HCV NS5A-transactivated protein 13; Nucleolar 130 kDa protein; Nucleolar pho
实测条带: 74,130KD(Nucleolar phosphoprotein p130)
功能: function:Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.,PTM:Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting that CDC2 kinase phosphorylates p130 at the M-phase.,similarity:Contains 1 LisH domain.,subcellular location:Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.,subunit:Interacts with RNA polymerase I 194 kDa subunit (RPA194) and with casein kinase-II.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus, nucleolus . Cytoplasm . Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase. .
组织表达: Bone marrow,Epithelium,Leukemia,Liver,Lung,Placenta,T-cell,
其他名称: NOLC1; KIAA0035; NS5ATP13; Nucleolar and coiled-body phosphoprotein 1; 140 kDa nucleolar phosphoprotein; Nopp140; Hepatitis C virus NS5A-transactivated protein 13; HCV NS5A-transactivated protein 13; Nucleolar 130 kDa protein; Nucleolar pho
实测条带: 74,130KD(Nucleolar phosphoprotein p130)
功能: function:Related to nucleologenesis, may play a role in the maintenance of the fundamental structure of the fibrillar center and dense fibrillar component in the nucleolus. It has intrinsic GTPase and ATPase activities. May play an important role in transcription catalyzed by RNA polymerase I.,PTM:Undergoes rapid and massive phosphorylation/dephosphorylation cycles on CK2 and PKC sites. There is evidence suggesting that CDC2 kinase phosphorylates p130 at the M-phase.,similarity:Contains 1 LisH domain.,subcellular location:Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase.,subunit:Interacts with RNA polymerase I 194 kDa subunit (RPA194) and with casein kinase-II.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Nucleus, nucleolus . Cytoplasm . Shuttles between the nucleolus and the cytoplasm. At telophase it begins to assemble into granular-like pre-nucleolar bodies which are subsequently relocated to nucleoli at the early G1-phase. .
组织表达: Bone marrow,Epithelium,Leukemia,Liver,Lung,Placenta,T-cell,