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NHE-6 Polyclonal Antibody
商品货号: PLA017105
适 应 性: 人,小鼠
WB ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: SLC9A6
  • 蛋白名称: Sodium/hydrogen exchanger 6
  • Human_gene_id: 10479
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10479
  • Human_swiss_prot_no: Q92581
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q92581/entry
  • 特异性: NHE-6 Polyclonal Antibody detects endogenous levels of NHE-6 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: SLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na(+)/H(+) exchanger 6; NHE-6; Solute carrier family 9 member 6
  • 实测条带: 75kD
  • 信号通路: Cardiac muscle contraction;
  • 功能: caution:Was initially identified as a mitochondrial inner membrane protein (PubMed:9507001), but was later shown to be localized in early and recycling endosomes and not mitochondria (PubMed:11940519).,disease:Defects in SLC9A6 are the cause of mental retardation syndromic X-linked Christianson type (MRXSC) [MIM:300243]; also known as MRXS-Christianson or X-linked Angelman-like syndrome. The phenotype is characterized by profound mental retardation, epilepsy, ataxia, and microcephaly, and showed phenotypic overlap with Angelman syndrome.,function:Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subcellular location:Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.,tissue specificity:Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endosome membrane ; Multi-pass membrane protein . Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.; [Isoform 2]: Recycling endosome membrane ; Multi-pass membrane protein .
  • 组织表达: Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
  • 科研货号: PLA017105
NHE-6 Polyclonal Antibody
Catalog No PLA017105
Product information
  • 基因名称: SLC9A6
  • 蛋白名称: Sodium/hydrogen exchanger 6
  • Human_gene_id: 10479
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=10479
  • Human_swiss_prot_no: Q92581
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q92581/entry
  • 特异性: NHE-6 Polyclonal Antibody detects endogenous levels of NHE-6 protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. ELISA: 1:40000. Not yet tested in other applications.
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: SLC9A6; KIAA0267; NHE6; Sodium/hydrogen exchanger 6; Na(+)/H(+) exchanger 6; NHE-6; Solute carrier family 9 member 6
  • 实测条带: 75kD
  • 信号通路: Cardiac muscle contraction;
  • 功能: caution:Was initially identified as a mitochondrial inner membrane protein (PubMed:9507001), but was later shown to be localized in early and recycling endosomes and not mitochondria (PubMed:11940519).,disease:Defects in SLC9A6 are the cause of mental retardation syndromic X-linked Christianson type (MRXSC) [MIM:300243]; also known as MRXS-Christianson or X-linked Angelman-like syndrome. The phenotype is characterized by profound mental retardation, epilepsy, ataxia, and microcephaly, and showed phenotypic overlap with Angelman syndrome.,function:Electroneutral exchange of protons for Na(+) and K(+) across the early and recycling endosome membranes. Contributes to calcium homeostasis.,similarity:Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family.,subcellular location:Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.,tissue specificity:Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Endosome membrane ; Multi-pass membrane protein . Is present in the recycling compartments including early and recycling endosomes, and only appears transiently on the plasma membrane.; [Isoform 2]: Recycling endosome membrane ; Multi-pass membrane protein .
  • 组织表达: Ubiquitous; but is most abundant in mitochondrion-rich tissues such as brain, skeletal muscle and heart.
  • 科研货号: PLA017105
  • Hunan UPT Biotechnology Co.,Ltd
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    E-mail:service@uptbio.com
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