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Neuro D Polyclonal Antibody
商品货号: PLA017070
适 应 性: 人,小鼠,大鼠
WB IHC ELISA
¥600元
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MSDS
说明书
商品描述
  • 基因名称: NEUROD1
  • 蛋白名称: Neurogenic differentiation factor 1
  • Human_gene_id: 4760
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4760
  • Human_swiss_prot_no: Q13562
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13562/entry
  • Mouse_gene_id: 18012
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18012
  • Mouse_swiss_prot_no: Q60867
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q60867
  • Rat_gene_id: 29458
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29458
  • Rat_swiss_prot_no: Q64289
  • Rat_swiss_link: http://www.uniprot.org/uniprot/Q64289
  • 特异性: Neuro D Polyclonal Antibody detects endogenous levels of Neuro D protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: NEUROD1; BHLHA3; NEUROD; Neurogenic differentiation factor 1; NeuroD; NeuroD1; Class A basic helix-loop-helix protein 3; bHLHa3
  • 实测条带: 36kD
  • 信号通路: Maturity onset diabetes of the young;
  • 功能: disease:Defects in NEUROD1 are the cause of maturity onset diabetes of the young type 6 (MODY6) [MIM:606394]. MODY [MIM:606391] is characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.,function:Differentiation factor required for dendrite morphogenesis and maintenance in the cerebellar cortex. Transcriptional activator. Binds to the insulin gene E-box.,PTM:Phosphorylated. In islet cells, phosphorylated on Ser-274 upon glucose stimulation; which may be required for nuclear localization. In activated neurons, phosphorylated on Ser-335; which promotes dendritic growth.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Heterodimer with TCF3/E47. Interacts with RREB1.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. .
  • 组织表达: Eye,Retina,Rhabdomyosarcoma,
  • 科研货号: PLA017070
Neuro D Polyclonal Antibody
Catalog No PLA017070
Product information
  • 基因名称: NEUROD1
  • 蛋白名称: Neurogenic differentiation factor 1
  • Human_gene_id: 4760
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4760
  • Human_swiss_prot_no: Q13562
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/Q13562/entry
  • Mouse_gene_id: 18012
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18012
  • Mouse_swiss_prot_no: Q60867
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/Q60867
  • Rat_gene_id: 29458
  • Rat_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29458
  • Rat_swiss_prot_no: Q64289
  • Rat_swiss_link: http://www.uniprot.org/uniprot/Q64289
  • 特异性: Neuro D Polyclonal Antibody detects endogenous levels of Neuro D protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500-2000;IHC-p 1:50-300; ELISA 2000-20000
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: NEUROD1; BHLHA3; NEUROD; Neurogenic differentiation factor 1; NeuroD; NeuroD1; Class A basic helix-loop-helix protein 3; bHLHa3
  • 实测条带: 36kD
  • 信号通路: Maturity onset diabetes of the young;
  • 功能: disease:Defects in NEUROD1 are the cause of maturity onset diabetes of the young type 6 (MODY6) [MIM:606394]. MODY [MIM:606391] is characterized by an autosomal dominant mode of inheritance, onset during young adulthood and a primary defect in insulin secretion.,function:Differentiation factor required for dendrite morphogenesis and maintenance in the cerebellar cortex. Transcriptional activator. Binds to the insulin gene E-box.,PTM:Phosphorylated. In islet cells, phosphorylated on Ser-274 upon glucose stimulation; which may be required for nuclear localization. In activated neurons, phosphorylated on Ser-335; which promotes dendritic growth.,similarity:Contains 1 basic helix-loop-helix (bHLH) domain.,subunit:Efficient DNA binding requires dimerization with another bHLH protein. Heterodimer with TCF3/E47. Interacts with RREB1.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cytoplasm . Nucleus . In pancreatic islet cells, shuttles to the nucleus in response to glucose stimulation (By similarity). Colocalizes with NR0B2 in the nucleus. .
  • 组织表达: Eye,Retina,Rhabdomyosarcoma,
  • 科研货号: PLA017070
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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