Neuralized-2 Polyclonal Antibody

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商品货号： PLA017062

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NEURL2
蛋白名称： Neuralized-like protein 2
Human_gene_id： 140825
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140825
Human_swiss_prot_no： Q9BR09
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BR09/entry
Mouse_swiss_prot_no： Q9D0S4
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D0S4
特异性： Neuralized-2 Polyclonal Antibody detects endogenous levels of Neuralized-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NEURL2; C20orf163; Neuralized-like protein 2
实测条带： 36kD
功能： domain:The SOCS domain mediates the interaction with TCEB1 and TCEB2, while the NHR domain may be involved in ubiquitination substrate binding.,function:Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 NHR (neuralized homology repeat) domain.,similarity:Contains 1 SOCS box domain.,subunit:Probable component the ECS(NEURL2) E3 ubiquitin-protein ligase complex consisting of TCEB2/Elongin B, TCEB1/Elongin C, CUL5, RBX1 and NEURL2. Interacts with CTNNB1.,tissue specificity:Expressed specifically in skeletal and cardiac muscles.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： Expressed specifically in skeletal and cardiac muscles.
科研货号： PLA017062

Neuralized-2 Polyclonal Antibody

Catalog No PLA017062

Product information

基因名称： NEURL2
蛋白名称： Neuralized-like protein 2
Human_gene_id： 140825
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=140825
Human_swiss_prot_no： Q9BR09
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q9BR09/entry
Mouse_swiss_prot_no： Q9D0S4
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q9D0S4
特异性： Neuralized-2 Polyclonal Antibody detects endogenous levels of Neuralized-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NEURL2; C20orf163; Neuralized-like protein 2
实测条带： 36kD
功能： domain:The SOCS domain mediates the interaction with TCEB1 and TCEB2, while the NHR domain may be involved in ubiquitination substrate binding.,function:Plays an important role in the process of myofiber differentiation and maturation. Probable substrate-recognition component of a SCF-like ECS (Elongin BC-CUL2/5-SOCS-box protein) E3 ubiquitin-protein ligase complex, which mediates the ubiquitination of proteins. Probably contributes to catalysis through recognition and positioning of the substrate and the ubiquitin-conjugating enzyme. During myogenesis, controls the ubiquitination and degradation of the specific pool of CTNNB1/beta-catenin located at the sarcolemma.,pathway:Protein modification; protein ubiquitination.,similarity:Contains 1 NHR (neuralized homology repeat) domain.,similarity:Contains 1 SOCS box domain.,subunit:Probable component the ECS(NEURL2) E3 ubiquitin-protein ligase complex consisting of TCEB2/Elongin B, TCEB1/Elongin C, CUL5, RBX1 and NEURL2. Interacts with CTNNB1.,tissue specificity:Expressed specifically in skeletal and cardiac muscles.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm .
组织表达： Expressed specifically in skeletal and cardiac muscles.
科研货号： PLA017062

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