Nephrocystin-4 Polyclonal Antibody

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商品货号： PLA017053

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NPHP4
蛋白名称： Nephrocystin-4
Human_gene_id： 261734
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=261734
Human_swiss_prot_no： O75161
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75161/entry
Mouse_swiss_prot_no： P59240
Mouse_swiss_link： http://www.uniprot.org/uniprot/P59240
特异性： Nephrocystin-4 Polyclonal Antibody detects endogenous levels of Nephrocystin-4 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin
分子量： 158kD
功能： disease:Defects in NPHP4 are the cause of nephronophthisis type 4 (NPHP4) [MIM:606966]; also known as familial juvenile nephronophthisis 4. NPHP4 is an autosomal recessive inherited disease resulting in end-stage renal disease at age ranging between 6 and 35 years. It is a progressive tubulo-interstitial kidney disorder characterized by polydipsia, polyuria, anemia and growth retardation. The most prominent histological features are modifications of the tubules with thickening of the basement membrane, interstitial fibrosis and, in the advanced stages, medullary cysts.,disease:Defects in NPHP4 are the cause of Senior-Loken syndrome type 4 (SLSN4) [MIM:606996]. SLSN is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney, with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.,similarity:Belongs to the NPHP4 family.,subunit:Interacts with NPHP1 and RPGRIP1L.,tissue specificity:Expressed in kidney, skeletal muscle, heart and liver, and to a lesser extent in brain and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, tight junction . Nucleus . In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions (By similarity). Localizes to the ciliary transition zone (By similarity). In the retinal photoreceptor cell layer, localizes at the connecting cilium (By similarity). .
组织表达： Expressed in kidney, skeletal muscle, heart and liver, and to a lesser extent in brain and lung.
科研货号： PLA017053

Nephrocystin-4 Polyclonal Antibody

Catalog No PLA017053

Product information

基因名称： NPHP4
蛋白名称： Nephrocystin-4
Human_gene_id： 261734
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=261734
Human_swiss_prot_no： O75161
Human_swiss_link： http://www.uniprot.org/uniprotkb/O75161/entry
Mouse_swiss_prot_no： P59240
Mouse_swiss_link： http://www.uniprot.org/uniprot/P59240
特异性： Nephrocystin-4 Polyclonal Antibody detects endogenous levels of Nephrocystin-4 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. ELISA: 1:40000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NPHP4; KIAA0673; Nephrocystin-4; Nephroretinin
分子量： 158kD
功能： disease:Defects in NPHP4 are the cause of nephronophthisis type 4 (NPHP4) [MIM:606966]; also known as familial juvenile nephronophthisis 4. NPHP4 is an autosomal recessive inherited disease resulting in end-stage renal disease at age ranging between 6 and 35 years. It is a progressive tubulo-interstitial kidney disorder characterized by polydipsia, polyuria, anemia and growth retardation. The most prominent histological features are modifications of the tubules with thickening of the basement membrane, interstitial fibrosis and, in the advanced stages, medullary cysts.,disease:Defects in NPHP4 are the cause of Senior-Loken syndrome type 4 (SLSN4) [MIM:606996]. SLSN is a renal-retinal disorder characterized by progressive wasting of the filtering unit of the kidney, with or without medullary cystic renal disease, and progressive eye disease. Typically this disorder becomes apparent during the first year of life.,similarity:Belongs to the NPHP4 family.,subunit:Interacts with NPHP1 and RPGRIP1L.,tissue specificity:Expressed in kidney, skeletal muscle, heart and liver, and to a lesser extent in brain and lung.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm, cytoskeleton, cilium basal body . Cytoplasm, cytoskeleton, microtubule organizing center, centrosome . Cell junction, tight junction . Nucleus . In cultured renal cells, it localizes diffusely in the cytoplasm but, as cells approach confluence, it accumulates to basolateral tight junctions (By similarity). Localizes to the ciliary transition zone (By similarity). In the retinal photoreceptor cell layer, localizes at the connecting cilium (By similarity). .
组织表达： Expressed in kidney, skeletal muscle, heart and liver, and to a lesser extent in brain and lung.
科研货号： PLA017053

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