Neddylin Polyclonal Antibody

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商品货号： PLA017042

适应性： 人,小鼠,大鼠,猴

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NEDD8
蛋白名称： NEDD8
Human_gene_id： 4738
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4738
Human_swiss_prot_no： Q15843
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q15843/entry
Mouse_gene_id： 18002
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18002
Mouse_swiss_prot_no： P29595
Mouse_swiss_link： http://www.uniprot.org/uniprot/P29595
Rat_gene_id： 25490
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25490
Rat_swiss_prot_no： Q71UE8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q71UE8
特异性： Neddylin Polyclonal Antibody detects endogenous levels of Neddylin protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NEDD8; NEDD8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8
实测条带： 9kD
功能： function:Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.,PTM:Cleavage of precursor form by UCHL3 or SENP8 is necessary for function.,similarity:Belongs to the ubiquitin family.,subcellular location:Mainly nuclear.,subunit:Directly interacts with NUB1 and AHR. Covalently attached to cullins and p53.,tissue specificity:Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Mainly nuclear. .
组织表达： Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
科研货号： PLA017042

Neddylin Polyclonal Antibody

Catalog No PLA017042

Product information

基因名称： NEDD8
蛋白名称： NEDD8
Human_gene_id： 4738
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4738
Human_swiss_prot_no： Q15843
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q15843/entry
Mouse_gene_id： 18002
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=18002
Mouse_swiss_prot_no： P29595
Mouse_swiss_link： http://www.uniprot.org/uniprot/P29595
Rat_gene_id： 25490
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25490
Rat_swiss_prot_no： Q71UE8
Rat_swiss_link： http://www.uniprot.org/uniprot/Q71UE8
特异性： Neddylin Polyclonal Antibody detects endogenous levels of Neddylin protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NEDD8; NEDD8; Neddylin; Neural precursor cell expressed developmentally down-regulated protein 8; NEDD-8; Ubiquitin-like protein Nedd8
实测条带： 9kD
功能： function:Ubiquitin-like protein which plays an important role in cell cycle control and embryogenesis. Covalent attachment to its substrates requires prior activation by the E1 complex UBE1C-APPBP1 and linkage to the E2 enzyme UBE2M. Attachment of NEDD8 to cullins activates their associated E3 ubiquitin ligase activity, and thus promotes polyubiquitination and proteasomal degradation of cyclins and other regulatory proteins.,PTM:Cleavage of precursor form by UCHL3 or SENP8 is necessary for function.,similarity:Belongs to the ubiquitin family.,subcellular location:Mainly nuclear.,subunit:Directly interacts with NUB1 and AHR. Covalently attached to cullins and p53.,tissue specificity:Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Nucleus . Mainly nuclear. .
组织表达： Highly expressed in heart, skeletal muscle, spleen, thymus, prostate, testis, ovary, colon and leukocytes.
科研货号： PLA017042

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