N/H/K-Ras Polyclonal Antibody

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商品货号： PLA016981

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： NRAS/HRAS/KRAS
蛋白名称： GTPase Nras/GTPase Hras/GTPase Kras
Human_gene_id： 3265/3845/4893
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3265
Human_swiss_prot_no： P01111/P01112/P01116
Human_swiss_link： http://www.uniprot.org/uniprotkb/P01111/entry
Mouse_gene_id： 15461/16653
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15461
Rat_gene_id： 24605/293621/24525
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24605
Rat_swiss_prot_no： Q04970/P20171/P08644
Rat_swiss_link： http://www.uniprot.org/uniprot/Q04970
特异性： N/H/K-Ras Polyclonal Antibody detects endogenous levels of N/H/K-Ras protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRAS; HRAS1; GTPase NRas; Transforming protein N-Ras; HRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; KRAS; KRAS2; RASK2; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras
实测条带： 21kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Chemokine;Axon guidance;VEGF;Tight junction;Gap junction;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Long-term potentiation;Neurotrophin;Long-term depression;Regulates Actin and Cytoskeleton;Insulin_Receptor;GnRH;Melanogenesis;Pathways in cancer;Renal cell carcinoma;Endometrial cancer;Glioma;Prostate cancer;Thyroid cancer;Melanoma;Bladder cancer;Chronic myeloid leukemia;Acute myeloid leukemia;Non-small cell lung cancer;
功能： disease:Defects in NRAS are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia.,disease:Mutations which change AA 12, 13 or 61 activate the potential of Ras to transform cultured cells and are implicated in a variety of human tumors.,enzyme regulation:Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).,function:Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.,online information:NRAS mutation db,online information:RAS proteins entry,PTM:Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:Shuttles between the plasma membrane and the Golgi apparatus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor . Shuttles between the plasma membrane and the Golgi apparatus. .
组织表达： Bone marrow,Bone-marrow,Brain,Fibrosarcoma,Kidney,Leukemia,Lung car
tag： hot
科研货号： PLA016981

N/H/K-Ras Polyclonal Antibody

Catalog No PLA016981

Product information

基因名称： NRAS/HRAS/KRAS
蛋白名称： GTPase Nras/GTPase Hras/GTPase Kras
Human_gene_id： 3265/3845/4893
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3265
Human_swiss_prot_no： P01111/P01112/P01116
Human_swiss_link： http://www.uniprot.org/uniprotkb/P01111/entry
Mouse_gene_id： 15461/16653
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=15461
Rat_gene_id： 24605/293621/24525
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=24605
Rat_swiss_prot_no： Q04970/P20171/P08644
Rat_swiss_link： http://www.uniprot.org/uniprot/Q04970
特异性： N/H/K-Ras Polyclonal Antibody detects endogenous levels of N/H/K-Ras protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC-p: 1:100-300 ELISA: 1:20000. IF 1:100-300 Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： NRAS; HRAS1; GTPase NRas; Transforming protein N-Ras; HRAS; HRAS1; GTPase HRas; H-Ras-1; Ha-Ras; Transforming protein p21; c-H-ras; p21ras; KRAS; KRAS2; RASK2; GTPase KRas; K-Ras 2; Ki-Ras; c-K-ras; c-Ki-ras
实测条带： 21kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;ErbB_HER;Chemokine;Axon guidance;VEGF;Tight junction;Gap junction;Natural killer cell mediated cytotoxicity;T_Cell_Receptor;B_Cell_Antigen;Fc epsilon RI;Long-term potentiation;Neurotrophin;Long-term depression;Regulates Actin and Cytoskeleton;Insulin_Receptor;GnRH;Melanogenesis;Pathways in cancer;Renal cell carcinoma;Endometrial cancer;Glioma;Prostate cancer;Thyroid cancer;Melanoma;Bladder cancer;Chronic myeloid leukemia;Acute myeloid leukemia;Non-small cell lung cancer;
功能： disease:Defects in NRAS are a cause of juvenile myelomonocytic leukemia (JMML) [MIM:607785]. JMML is a pediatric myelodysplastic syndrome that constitutes approximately 30% of childhood cases of myelodysplastic syndrome (MDS) and 2% of leukemia.,disease:Mutations which change AA 12, 13 or 61 activate the potential of Ras to transform cultured cells and are implicated in a variety of human tumors.,enzyme regulation:Alternate between an inactive form bound to GDP and an active form bound to GTP. Activated by a guanine nucleotide-exchange factor (GEF) and inactivated by a GTPase-activating protein (GAP).,function:Ras proteins bind GDP/GTP and possess intrinsic GTPase activity.,online information:NRAS mutation db,online information:RAS proteins entry,PTM:Palmitoylated by the ZDHHC9-GOLGA7 complex. A continuous cycle of de- and re-palmitoylation regulates rapid exchange between plasma membrane and Golgi.,similarity:Belongs to the small GTPase superfamily. Ras family.,subcellular location:Shuttles between the plasma membrane and the Golgi apparatus.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cell membrane ; Lipid-anchor ; Cytoplasmic side . Golgi apparatus membrane ; Lipid-anchor . Shuttles between the plasma membrane and the Golgi apparatus. .
组织表达： Bone marrow,Bone-marrow,Brain,Fibrosarcoma,Kidney,Leukemia,Lung car
tag： hot
科研货号： PLA016981

Hunan UPT Biotechnology Co.,Ltd

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