MYLIP Polyclonal Antibody

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商品货号： PLA016965

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MYLIP
蛋白名称： E3 ubiquitin-protein ligase MYLIP
Human_gene_id： 29116
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29116
Human_swiss_prot_no： Q8WY64
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8WY64/entry
Mouse_gene_id： 218203
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=218203
Mouse_swiss_prot_no： Q8BM54
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BM54
Rat_gene_id： 306825
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=306825
Rat_swiss_prot_no： D3ZDI6
Rat_swiss_link： http://www.uniprot.org/uniprot/D3ZDI6
特异性： MYLIP Polyclonal Antibody detects endogenous levels of MYLIP protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MYLIP; BZF1; IDOL; BM-023; PP5242; E3 ubiquitin-protein ligase MYLIP; Inducible degrader of the LDL-receptor; Idol; Myosin regulatory light chain interacting protein; MIR
实测条带： 50kD
功能： developmental stage:Expressed in fetal tissues and higher levels were detected in placenta and fetal lung.,domain:The RING domain mediates ubiquitination and the neurite outgrowth inhibitory activity.,function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC). Stable or transient overexpression of MIR induces proteasomal degradation of MRLC inhibiting neurite outgrowth in presence of NGF. MIR counteracts the stabilization of MRLC by MIR-interacting saposin-like protein (MSAP/TMEM4) and reduces MSAP-stimulated neurite outgrowth.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 FERM domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with myosin regulatory light chain (MRLC) and TMEM4.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein .
组织表达： Ubiquitously expressed.
科研货号： PLA016965

MYLIP Polyclonal Antibody

Catalog No PLA016965

Product information

基因名称： MYLIP
蛋白名称： E3 ubiquitin-protein ligase MYLIP
Human_gene_id： 29116
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=29116
Human_swiss_prot_no： Q8WY64
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q8WY64/entry
Mouse_gene_id： 218203
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=218203
Mouse_swiss_prot_no： Q8BM54
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q8BM54
Rat_gene_id： 306825
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=306825
Rat_swiss_prot_no： D3ZDI6
Rat_swiss_link： http://www.uniprot.org/uniprot/D3ZDI6
特异性： MYLIP Polyclonal Antibody detects endogenous levels of MYLIP protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:20000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MYLIP; BZF1; IDOL; BM-023; PP5242; E3 ubiquitin-protein ligase MYLIP; Inducible degrader of the LDL-receptor; Idol; Myosin regulatory light chain interacting protein; MIR
实测条带： 50kD
功能： developmental stage:Expressed in fetal tissues and higher levels were detected in placenta and fetal lung.,domain:The RING domain mediates ubiquitination and the neurite outgrowth inhibitory activity.,function:E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of myosin regulatory light chain (MRLC). Stable or transient overexpression of MIR induces proteasomal degradation of MRLC inhibiting neurite outgrowth in presence of NGF. MIR counteracts the stabilization of MRLC by MIR-interacting saposin-like protein (MSAP/TMEM4) and reduces MSAP-stimulated neurite outgrowth.,pathway:Protein modification; protein ubiquitination.,PTM:Autoubiquitinated.,similarity:Contains 1 FERM domain.,similarity:Contains 1 RING-type zinc finger.,subunit:Interacts with myosin regulatory light chain (MRLC) and TMEM4.,tissue specificity:Ubiquitously expressed.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Cell membrane ; Peripheral membrane protein .
组织表达： Ubiquitously expressed.
科研货号： PLA016965

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