功能: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane; Multi-pass membrane protein.
组织表达: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.
科研货号: PLA016873
MRGX1 Polyclonal Antibody
Catalog NoPLA016873
Product information
基因名称: MRGPRX1
蛋白名称: Mas-related G-protein coupled receptor member X1
功能: function:Orphan receptor. Probably involved in the function of nociceptive neurons. May regulate nociceptor function and/or development, including the sensation or modulation of pain. Potently activated by enkephalins including BAM22 (bovine adrenal medulla peptide 22) and BAM (8-22). BAM22 is the most potent compound and evoked a large and dose-dependent release of intracellular calcium in stably transfected cells. G(alpha)q proteins are involved in the calcium-signaling pathway.,similarity:Belongs to the G-protein coupled receptor 1 family. Mas subfamily.,tissue specificity:Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.,
相关产品: RS0001,RS0002,YM3028,YM3029
细胞定位: Cell membrane; Multi-pass membrane protein.
组织表达: Uniquely localized in a subset of small dorsal root and trigeminal sensory neurons.