其他名称： MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
分子量： 100-120kD
信号通路： Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; B_Cell_Antigen
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： intracellular,integral component of membrane,
组织表达： Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.
科研货号： PLA016828
MLK1/2 Polyclonal Antibody
Catalog NoPLA016828
Product information
基因名称： MAP3K9/MAP3K10
蛋白名称： Mitogen-activated protein kinase kinase kinase 9/10
其他名称： MAP3K9; MLK1; PRKE1; Mitogen-activated protein kinase kinase kinase 9; Mixed lineage kinase 1; MAP3K10; MLK2; MST; Mitogen-activated protein kinase kinase kinase 10; Mixed lineage kinase 2; Protein kinase MST
分子量： 100-120kD
信号通路： Regulation of Actin Dynamics; SAPK_JNK; Stem cell pathway; B_Cell_Antigen
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Homodimerization via the leucine zipper domains is required for autophosphorylation and subsequent activation.,function:Activates the JUN N-terminal pathway.,PTM:Autophosphorylation on serine and threonine residues within the activation loop plays a role in enzyme activation. Thr-312 is likely to be the main autophosphorylation site.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,similarity:Contains 1 SH3 domain.,subunit:Homodimer.,tissue specificity:Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： intracellular,integral component of membrane,
组织表达： Expressed in epithelial tumor cell lines of colonic, breast and esophageal origin.
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