信号通路： SAPK_JNK; Regulation of Actin Dynamics; Cell Growth; Stem cell pathway; Cell_Cycle_G1S;Cell_Cycle_G2M_DNA; MAPK_ERK_Growth;MAPK_G_Protein; B Cell Receptor
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-806. Catalytically active only when complexed with MAP3K5, with MAP3K5 supporting the stability and the active configuration of MAP3K6 and MAP3K6 activating MAP3K5 by direct phosphorylation.,function:Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds both upstream activators and downstream substrates in multimolecular complexes.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： intracellular,
组织表达： Brain,PCR rescued clones,Skin,
科研货号： PLA016768
MEK Kinase-6 Polyclonal Antibody
Catalog NoPLA016768
Product information
基因名称： MAP3K6
蛋白名称： Mitogen-activated protein kinase kinase kinase 6
信号通路： SAPK_JNK; Regulation of Actin Dynamics; Cell Growth; Stem cell pathway; Cell_Cycle_G1S;Cell_Cycle_G2M_DNA; MAPK_ERK_Growth;MAPK_G_Protein; B Cell Receptor
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-806. Catalytically active only when complexed with MAP3K5, with MAP3K5 supporting the stability and the active configuration of MAP3K6 and MAP3K6 activating MAP3K5 by direct phosphorylation.,function:Component of a protein kinase signal transduction cascade. Activates the JNK, but not ERK or p38 kinase pathways.,similarity:Belongs to the protein kinase superfamily.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 protein kinase domain.,subunit:Binds both upstream activators and downstream substrates in multimolecular complexes.,
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