MEK Kinase-3 Polyclonal Antibody

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商品货号： PLA016766

适应性： 人,小鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： MAP3K3
蛋白名称： Mitogen-activated protein kinase kinase kinase 3
Human_gene_id： 4215
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4215
Human_swiss_prot_no： Q99759
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q99759/entry
Mouse_gene_id： 26406
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26406
Mouse_swiss_prot_no： Q61084
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61084
特异性： MEK Kinase-3 Polyclonal Antibody detects endogenous levels of MEK Kinase-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MAP3K3; MAPKKK3; MEKK3; Mitogen-activated protein kinase kinase kinase 3; MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3
实测条带： 71kD
信号通路： Regulation of Actin Dynamics; SAPK_JNK; Cell Growth; Stem cell pathway; B Cell Receptor
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-530.,function:Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 OPR domain.,similarity:Contains 1 protein kinase domain.,subunit:Binds both upstream activators and downstream substrates in multimolecular complexes. Part of a complex with MAP2K3, RAC1 and CCM2. Interacts with MAP2K5 and SPAG9.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytoplasm,cytosol,
组织表达： Aorta,Brain,Epithelium,Kidney,Melanoma,Placenta,PNS
科研货号： PLA016766

MEK Kinase-3 Polyclonal Antibody

Catalog No PLA016766

Product information

基因名称： MAP3K3
蛋白名称： Mitogen-activated protein kinase kinase kinase 3
Human_gene_id： 4215
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=4215
Human_swiss_prot_no： Q99759
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q99759/entry
Mouse_gene_id： 26406
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=26406
Mouse_swiss_prot_no： Q61084
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61084
特异性： MEK Kinase-3 Polyclonal Antibody detects endogenous levels of MEK Kinase-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:20000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MAP3K3; MAPKKK3; MEKK3; Mitogen-activated protein kinase kinase kinase 3; MAPK/ERK kinase kinase 3; MEK kinase 3; MEKK 3
实测条带： 71kD
信号通路： Regulation of Actin Dynamics; SAPK_JNK; Cell Growth; Stem cell pathway; B Cell Receptor
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,cofactor:Magnesium.,enzyme regulation:Activated by phosphorylation on Thr-530.,function:Component of a protein kinase signal transduction cascade. Mediates activation of the NF-kappa-B, AP1 and DDIT3 transcriptional regulators.,similarity:Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.,similarity:Contains 1 OPR domain.,similarity:Contains 1 protein kinase domain.,subunit:Binds both upstream activators and downstream substrates in multimolecular complexes. Part of a complex with MAP2K3, RAC1 and CCM2. Interacts with MAP2K5 and SPAG9.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： cytoplasm,cytosol,
组织表达： Aorta,Brain,Epithelium,Kidney,Melanoma,Placenta,PNS
科研货号： PLA016766

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