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M-cadherin Polyclonal Antibody
商品货号: PLA016740
适 应 性: 人,小鼠,大鼠
WB IHC IF ELISA
¥600元
规格:
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MSDS
说明书
商品描述
  • 基因名称: CDH15
  • 蛋白名称: Cadherin-15
  • Human_gene_id: 1013
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1013
  • Human_swiss_prot_no: P55291
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P55291/entry
  • Mouse_gene_id: 12555
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12555
  • Mouse_swiss_prot_no: P33146
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P33146
  • 特异性: M-cadherin Polyclonal Antibody detects endogenous levels of M-cadherin protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
  • 实测条带: 89kD
  • 信号通路: Cell adhesion molecules (CAMs);
  • 功能: disease:A chromosomal aberration involving CDH15 and KIRREL3 is found in a patient with severe mental retardation and dysmorphic facial features. Translocation t(11;16)(q24.2;q24).,disease:Defects in CDH15 are the cause of mental retardation autosomal dominant type 3 (MRD3) [MIM:612580]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in the brain and cerebellum.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Single-pass type I membrane protein.
  • 组织表达: Expressed in the brain and cerebellum.
  • tag: hot
  • 科研货号: PLA016740
M-cadherin Polyclonal Antibody
Catalog No PLA016740
Product information
  • 基因名称: CDH15
  • 蛋白名称: Cadherin-15
  • Human_gene_id: 1013
  • Human_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=1013
  • Human_swiss_prot_no: P55291
  • Human_swiss_link: http://www.uniprot.org/uniprotkb/P55291/entry
  • Mouse_gene_id: 12555
  • Mouse_gene_link: http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=12555
  • Mouse_swiss_prot_no: P33146
  • Mouse_swiss_link: http://www.uniprot.org/uniprot/P33146
  • 特异性: M-cadherin Polyclonal Antibody detects endogenous levels of M-cadherin protein.
  • 组成: Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
  • 来源: Polyclonal, Rabbit,IgG
  • 稀释: WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:10000.. IF 1:50-200
  • 纯化工艺: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
  • 浓度: 1 mg/ml
  • 储存: -15°C to -25°C/1 year(Do not lower than -25°C)
  • 说明书: 1
  • Msds: MSDS_Antibody.pdf
  • 其他名称: CDH15; CDH14; CDH3; Cadherin-15; Cadherin-14; Muscle cadherin; M-cadherin
  • 实测条带: 89kD
  • 信号通路: Cell adhesion molecules (CAMs);
  • 功能: disease:A chromosomal aberration involving CDH15 and KIRREL3 is found in a patient with severe mental retardation and dysmorphic facial features. Translocation t(11;16)(q24.2;q24).,disease:Defects in CDH15 are the cause of mental retardation autosomal dominant type 3 (MRD3) [MIM:612580]. Mental retardation is characterized by significantly sub-average general intellectual functioning associated with impairments in adaptative behavior and manifested during the developmental period.,function:Cadherins are calcium dependent cell adhesion proteins. They preferentially interact with themselves in a homophilic manner in connecting cells; cadherins may thus contribute to the sorting of heterogeneous cell types. M-cadherin is part of the myogenic program and may provide a trigger for terminal muscle differentiation.,similarity:Contains 5 cadherin domains.,tissue specificity:Expressed in the brain and cerebellum.,
  • 相关产品: RS0001,RS0002,YM3028,YM3029
  • 细胞定位: Cell membrane; Single-pass type I membrane protein.
  • 组织表达: Expressed in the brain and cerebellum.
  • tag: hot
  • 科研货号: PLA016740
  • Hunan UPT Biotechnology Co.,Ltd
    Website:www.uptbio.com Servive hotline :4006916686
    E-mail:service@uptbio.com
    Address:
    Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.
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