MAPKAPK-2 Polyclonal Antibody

> > > >

商品货号： PLA016709

适应性： 人,小鼠,大鼠,猴

￥600元

规格：

40μL 100μL 200μL

在线咨询

MSDS

说明书

商品描述

基因名称： MAPKAPK2
蛋白名称： MAP kinase-activated protein kinase 2
Human_gene_id： 9261
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9261
Human_swiss_prot_no： P49137
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49137/entry
Mouse_gene_id： 17164
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17164
Mouse_swiss_prot_no： P49138
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49138
特异性： MAPKAPK-2 Polyclonal Antibody detects endogenous levels of MAPKAPK-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MAPKAPK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2
实测条带： 46kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;VEGF;Neurotrophin;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Seems to be activated by two distinct pathways: the first involves the stimulation of p42/p44 MAPK by growth factors, the second, triggered by stress and heat shock, depends on the activation of MPK2 and upstream MAPKK/MAPKKK.,function:Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.,PTM:Phosphorylated and activated by MAP kinase.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with PHC2.,tissue specificity:Expressed in all tissues examined.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Phosphorylation and subsequent activation releases the autoinhibitory helix, resulting in the export from the nucleus into the cytoplasm.
组织表达： Expressed in all tissues examined.
科研货号： PLA016709

MAPKAPK-2 Polyclonal Antibody

Catalog No PLA016709

Product information

基因名称： MAPKAPK2
蛋白名称： MAP kinase-activated protein kinase 2
Human_gene_id： 9261
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=9261
Human_swiss_prot_no： P49137
Human_swiss_link： http://www.uniprot.org/uniprotkb/P49137/entry
Mouse_gene_id： 17164
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=17164
Mouse_swiss_prot_no： P49138
Mouse_swiss_link： http://www.uniprot.org/uniprot/P49138
特异性： MAPKAPK-2 Polyclonal Antibody detects endogenous levels of MAPKAPK-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： MAPKAPK2; MAP kinase-activated protein kinase 2; MAPK-activated protein kinase 2; MAPKAP kinase 2; MAPKAP-K2; MAPKAPK-2; MK-2; MK2
实测条带： 46kD
信号通路： MAPK_ERK_Growth;MAPK_G_Protein;VEGF;Neurotrophin;
功能： catalytic activity:ATP + a protein = ADP + a phosphoprotein.,enzyme regulation:Seems to be activated by two distinct pathways: the first involves the stimulation of p42/p44 MAPK by growth factors, the second, triggered by stress and heat shock, depends on the activation of MPK2 and upstream MAPKK/MAPKKK.,function:Its physiological substrate seems to be the small heat shock protein (HSP27/HSP25). In vitro can phosphorylate glycogen synthase at 'Ser-7' and tyrosine hydroxylase (on 'Ser-19' and 'Ser-40'). This kinase phosphorylates Ser in the peptide sequence, Hyd-X-R-X(2)-S, where Hyd is a large hydrophobic residue (By similarity). Mediates both ERK and p38 MAPK/MAPK14 dependent neutrophil responses. Participates in TNF alpha-stimulated exocytosis of secretory vesicles in neutrophils. Plays a role in phagocytosis-induced respiratory burst activity.,PTM:Phosphorylated and activated by MAP kinase.,similarity:Belongs to the protein kinase superfamily. CAMK Ser/Thr protein kinase family.,similarity:Contains 1 protein kinase domain.,subunit:Interacts with PHC2.,tissue specificity:Expressed in all tissues examined.,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Cytoplasm . Nucleus . Phosphorylation and subsequent activation releases the autoinhibitory helix, resulting in the export from the nucleus into the cytoplasm.
组织表达： Expressed in all tissues examined.
科研货号： PLA016709

Hunan UPT Biotechnology Co.,Ltd

Website：www.uptbio.com Servive hotline :4006916686

E-mail：service@uptbio.com

Address：

Room 402, Building 13, Xinggong International Industrial Park, 100 Guyuan Road, Yuelu District, Changsha City, Hunan Province, China.