Laminin β-3 Polyclonal Antibody

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商品货号： PLA016609

适应性： 人,大鼠,小鼠,

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： LAMB3
蛋白名称： Laminin subunit beta-3
Human_gene_id： 3914
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3914
Human_swiss_prot_no： Q13751
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13751/entry
Mouse_swiss_prot_no： Q61087
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61087
特异性： Laminin β-3 Polyclonal Antibody detects endogenous levels of Laminin β-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： LAMB3; LAMNB1; Laminin subunit beta-3; Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta
分子量： 130kD
信号通路： Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能： disease:Defects in LAMB3 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB) [MIM:226700]; also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth and extensive denudation of skin and mucous membranes that may be hemorrhagic.,disease:Defects in LAMB3 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB) [MIM:226650]. GABEB is a non-lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities.,domain:Domain VI is globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 6 laminin EGF-like domains.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-3 is a subunit of laminin-5 (epiligrin/kalinin/nicein).,tissue specificity:Found in the basement membranes (major component).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix, basement membrane.
组织表达： Found in the basement membranes (major component).
科研货号： PLA016609

Laminin β-3 Polyclonal Antibody

Catalog No PLA016609

Product information

基因名称： LAMB3
蛋白名称： Laminin subunit beta-3
Human_gene_id： 3914
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3914
Human_swiss_prot_no： Q13751
Human_swiss_link： http://www.uniprot.org/uniprotkb/Q13751/entry
Mouse_swiss_prot_no： Q61087
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61087
特异性： Laminin β-3 Polyclonal Antibody detects endogenous levels of Laminin β-3 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： IHC 1:100 - 1:300. IF 1:200 - 1:1000. ELISA: 1:5000. Not yet tested in other applications.
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： LAMB3; LAMNB1; Laminin subunit beta-3; Epiligrin subunit bata; Kalinin B1 chain; Kalinin subunit beta; Laminin B1k chain; Laminin-5 subunit beta; Nicein subunit beta
分子量： 130kD
信号通路： Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能： disease:Defects in LAMB3 are a cause of epidermolysis bullosa junctional Herlitz type (H-JEB) [MIM:226700]; also known as junctional epidermolysis bullosa Herlitz-Pearson type. JEB defines a group of blistering skin diseases characterized by tissue separation which occurs within the dermo-epidermal basement membrane. H-JEB is a severe, infantile and lethal form. Death occurs usually within the first six months of life. Occasionally, children survive to teens. H-JEB is marked by bullous lesions at birth and extensive denudation of skin and mucous membranes that may be hemorrhagic.,disease:Defects in LAMB3 are a cause of generalized atrophic benign epidermolysis bullosa (GABEB) [MIM:226650]. GABEB is a non-lethal, adult form of junctional epidermolysis bullosa characterized by life-long blistering of the skin, associated with hair and tooth abnormalities.,domain:Domain VI is globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 6 laminin EGF-like domains.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-3 is a subunit of laminin-5 (epiligrin/kalinin/nicein).,tissue specificity:Found in the basement membranes (major component).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix, basement membrane.
组织表达： Found in the basement membranes (major component).
科研货号： PLA016609

Hunan UPT Biotechnology Co.,Ltd

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