Laminin β-2 Polyclonal Antibody

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商品货号： PLA016608

适应性： 人,小鼠,大鼠

￥600元

规格：

40μL 100μL 200μL

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MSDS

说明书

商品描述

基因名称： LAMB2
蛋白名称： Laminin subunit beta-2
Human_gene_id： 3913
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3913
Human_swiss_prot_no： P55268
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55268/entry
Mouse_gene_id： 16779
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16779
Mouse_swiss_prot_no： Q61292
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61292
Rat_gene_id： 25473
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25473
Rat_swiss_prot_no： P15800
Rat_swiss_link： http://www.uniprot.org/uniprot/P15800
特异性： Laminin β-2 Polyclonal Antibody detects endogenous levels of Laminin β-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： LAMB2; LAMS; Laminin subunit beta-2; Laminin B1s chain; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin sub
实测条带： 210kD
信号通路： Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能： disease:Defects in LAMB2 are a cause of congenital nephrotic syndrome [MIM:609049]. Congenital nephrotic syndrome constitutes a heterogeneous group of conditions having in common the disruption of normal glomerular permselectivity. Congenital nephrotic syndrome due to LAMB2 mutations may be associated with ocular abnormalities.,disease:Defects in LAMB2 are the cause of Pierson syndrome [MIM:609049]; also known as microcoria-congenital nephrotic syndrome. Pierson syndrome is characterized by nephrotic syndrome with neonatal onset, diffuse mesangial sclerosis and eye abnormalities with microcoria as the leading clinical feature. Death usually occurs within the first weeks of life. Disease severity depends on the mutation type: nontruncating LAMB2 mutations may display variable phenotypes ranging from a milder variant of Pierson syndrome to isolated congenital nephrotic syndrome.,domain:Domains VI and IV are globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type B domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 13 laminin EGF-like domains.,subcellular location:S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-2 is a subunit of laminin-3 (S-laminin), laminin-4 (S-merosin), and laminin-7 (KS-laminin).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix, basement membrane. S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.
组织表达： Liver,Placenta,Uterus,
科研货号： PLA016608

Laminin β-2 Polyclonal Antibody

Catalog No PLA016608

Product information

基因名称： LAMB2
蛋白名称： Laminin subunit beta-2
Human_gene_id： 3913
Human_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=3913
Human_swiss_prot_no： P55268
Human_swiss_link： http://www.uniprot.org/uniprotkb/P55268/entry
Mouse_gene_id： 16779
Mouse_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=16779
Mouse_swiss_prot_no： Q61292
Mouse_swiss_link： http://www.uniprot.org/uniprot/Q61292
Rat_gene_id： 25473
Rat_gene_link： http://www.ncbi.nlm.nih.gov/sites/entrez?db=gene&term=25473
Rat_swiss_prot_no： P15800
Rat_swiss_link： http://www.uniprot.org/uniprot/P15800
特异性： Laminin β-2 Polyclonal Antibody detects endogenous levels of Laminin β-2 protein.
组成： Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
来源： Polyclonal, Rabbit,IgG
稀释： WB 1:500 - 1:2000. IHC 1:100 - 1:300. ELISA: 1:5000.. IF 1:50-200
纯化工艺： The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
浓度： 1 mg/ml
储存： -15°C to -25°C/1 year(Do not lower than -25°C)
说明书： 1
Msds： MSDS_Antibody.pdf
其他名称： LAMB2; LAMS; Laminin subunit beta-2; Laminin B1s chain; Laminin-11 subunit beta; Laminin-14 subunit beta; Laminin-15 subunit beta; Laminin-3 subunit beta; Laminin-4 subunit beta; Laminin-7 subunit beta; Laminin-9 subunit beta; S-laminin sub
实测条带： 210kD
信号通路： Focal adhesion;ECM-receptor interaction;Pathways in cancer;Small cell lung cancer;
功能： disease:Defects in LAMB2 are a cause of congenital nephrotic syndrome [MIM:609049]. Congenital nephrotic syndrome constitutes a heterogeneous group of conditions having in common the disruption of normal glomerular permselectivity. Congenital nephrotic syndrome due to LAMB2 mutations may be associated with ocular abnormalities.,disease:Defects in LAMB2 are the cause of Pierson syndrome [MIM:609049]; also known as microcoria-congenital nephrotic syndrome. Pierson syndrome is characterized by nephrotic syndrome with neonatal onset, diffuse mesangial sclerosis and eye abnormalities with microcoria as the leading clinical feature. Death usually occurs within the first weeks of life. Disease severity depends on the mutation type: nontruncating LAMB2 mutations may display variable phenotypes ranging from a milder variant of Pierson syndrome to isolated congenital nephrotic syndrome.,domain:Domains VI and IV are globular.,domain:The alpha-helical domains I and II are thought to interact with other laminin chains to form a coiled coil structure.,function:Binding to cells via a high affinity receptor, laminin is thought to mediate the attachment, migration and organization of cells into tissues during embryonic development by interacting with other extracellular matrix components.,similarity:Contains 1 laminin IV type B domain.,similarity:Contains 1 laminin N-terminal domain.,similarity:Contains 13 laminin EGF-like domains.,subcellular location:S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.,subunit:Laminin is a complex glycoprotein, consisting of three different polypeptide chains (alpha, beta, gamma), which are bound to each other by disulfide bonds into a cross-shaped molecule comprising one long and three short arms with globules at each end. Beta-2 is a subunit of laminin-3 (S-laminin), laminin-4 (S-merosin), and laminin-7 (KS-laminin).,
相关产品： RS0001,RS0002,YM3028,YM3029
细胞定位： Secreted, extracellular space, extracellular matrix, basement membrane. S-laminin is concentrated in the synaptic cleft of the neuromuscular junction.
组织表达： Liver,Placenta,Uterus,
科研货号： PLA016608

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